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Comparison of Abbott RealTime HCV Genotype II with Versant Line Probe Assay 2.0 for Hepatitis C Virus Genotyping

机译:雅培实时HCV基因型II与Versant线探针测定2.0用于丙型肝炎病毒基因分型的比较

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Genotyping and subtyping of 225 samples with hepatitis C virus (HCV) genotype 1, 2, 3, or 6 infection were done with Versant LiPA 2.0 and Abbott RealTime HCV Genotype (GT) II by using direct sequencing of the NS5B and 5′ untranslated regions as the reference standards. The concordance rates were >99.2% for genotypes and 96.1% for subtypes 1a and 1b. Both the Abbott RealTime and Versant LiPA assays can accurately determine hepatitis C virus genotypes. (This study has been registered at ClinicalTrials.gov under registration no. NCT00979979.)
机译:使用Versant LiPA 2.0和Abbott RealTime HCV基因型(GT)II,通过对NS5B和5'非翻译区进行直接测序,对225个感染了1、2、3或6型丙型肝炎病毒(HCV)基因型的样本进行了基因分型和分型作为参考标准。基因型的一致性率> 99.2%,亚型1a和1b的一致性率为96.1%。 Abbott RealTime和Versant LiPA分析均可准确确定丙型肝炎病毒的基因型。 (此研究已在ClinicalTrials.gov上注册,注册号为NCT00979979。)

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