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Phaeohyphomycosis Caused by a Novel Species, Pseudochaetosphaeronema martinelli

机译:一种新物种引起的致萎缩性真菌病,马氏假单胞菌

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Among the opportunistic mycoses that are emerging in patients with immunosuppression or severe underlying illness, many isolates lack of characteristic sporulation and until recently could not be identified. Clinical signs are mostly nonspecific and therefore such infections have often been disregarded. In the present paper we describe a novel, nonsporulating fungal species causing subcutaneous phaeohyphomycosis in two patients of different origin. One is a 73-year-old female from Martinique who suffered from rheumatoid arthritis, while the other case concerns a 72-year-old male from Mexico who had a history of type 2 diabetes mellitus. Sequencing of the partial ribosomal operon revealed that in both cases a member of the order Pleosporales was concerned which could not be affiliated to any family within this order. Multilocus analysis revealed that the fungus was related to another, unaffiliated agent of human mycetoma, Pseudochaetosphaeronema larense, and therefore the name Pseudochaetosphaeronema martinelli was introduced.
机译:在免疫抑制或严重基础疾病患者中出现的机会性霉菌病中,许多分离株缺乏特征性孢子形成,直到最近才被发现。临床体征大多是非特异性的,因此经常忽略这种感染。在本文中,我们描述了一种新的,非孢子化的真菌物种,该真菌物种在两名不同血统的患者中引起皮下疏霉菌病。一个是马提尼克岛的一名73岁女性,患有类风湿性关节炎,另一例是墨西哥的一名72岁男性,患有2型糖尿病。对部分核糖体操纵子的测序表明,在这两种情况下,都涉及到了猪胸骨目中的一个成员,该成员不能隶属于该顺序中的任何家庭。多基因座分析表明,该真菌与人肌瘤的另一种非亲缘关系紧密相关,因此引入了马氏假单胞菌。

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