Diagnosis of Clostridium difficile Infections in Children

Stella Antonara; Amy L. Leber

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Diagnosis of Clostridium difficile Infections in Children

机译：小儿艰难梭菌感染的诊断

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The detection and diagnosis of Clostridium difficile infection in pediatric populations have some unique considerations in comparison to testing in adults. The testing methodologies, including toxigenic culture, cell cytotoxicity, antigen detection, and, more recently, molecular testing, are the same in all age groups. However, limited data exist on the specific performance characteristics in children. In this review, we focus on the challenges of testing in pediatric populations and assess the available data on test performance in these populations. Additionally, a review of the existing guidance for testing is provided.

机译：与成人测试相比，在儿科人群中艰难梭菌感染的检测和诊断有一些独特的考虑因素。在所有年龄段，包括产毒培养，细胞毒性，抗原检测以及最近的分子检测在内的检测方法均相同。但是，关于儿童具体表现特征的数据有限。在本文中，我们将重点放在儿科人群的测试挑战上，并评估这些人群的测试表现的可用数据。此外，还提供了对现有测试指南的审查。

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《Journal of Clinical Microbiology》 |2016年第6期|共9页
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Stella Antonara; Amy L. Leber;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Diagnostic des infections a Clostridium difficile Clostridium difficile infection diagnosis [J] . C. Eckert, V. Lalande, F. Barbut Journal des anti-infectieux . 2011,第2期

机译：艰难梭菌感染的诊断诊断艰难梭菌感染的诊断
2. Rapid detection of Clostridium difficile toxins and laboratory diagnosis of Clostridium difficile infections [J] . Chen Shuyi, Gu Huawei, Sun Chunli, Infection . 2017,第3期

机译：快速检测梭菌艰难毒素和实验室诊断梭菌腹菌感染
3. Variability in testing policies and impact on reported Clostridium difficile infection rates: results from the pilot Longitudinal European Clostridium difficile Infection Diagnosis surveillance study (LuCID) [J] . Davies K., Davis G., Barbut F., European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2016,第12期

机译：测试政策的差异及其对报告的难辨梭状芽胞杆菌感染率的影响：欧洲纵向难辨梭状芽胞杆菌感染诊断监测研究（LuCID）的初步结果
4. CREST - Risk Prediction for Clostridium Difficile Infection Using Multimodal Data Mining [C] . Cansu Sen, Thomas Hartvigsen, Elke Rundensteiner, European conference on machine learning and principles and practice of knowledge discovery in databases . 2017

机译：CREST-使用多模式数据挖掘的艰难梭菌感染风险预测
5. A Possible Role of Clostridium difficile Association with the GI Tract in Relapsing Clostridium difficile Infection [D] . Ashraf, Asiyya 2019

机译：难辨梭状芽胞杆菌与胃肠道的关联在复发性难辨梭状芽胞杆菌感染中的可能作用
6. Variability in testing policies and impact on reported Clostridium difficile infection rates: results from the pilot Longitudinal European Clostridium difficile Infection Diagnosis surveillance study (LuCID) [O] . K. Davies, G. Davis, F. Barbut, -1

机译：测试政策的差异及其对报告的艰难梭菌感染率的影响：欧洲纵向难辨梭状芽胞杆菌感染诊断监测试验（LuCID）的初步结果
7. Variability in testing policies and impact on reported Clostridium difficile infection rates: results from the pilot Longitudinal European Clostridium difficile Infection Diagnosis surveillance study (LuCID) [O] . Davies K, Davis G, Barbut F, 2016

机译：测试政策的变异性和对报告的艰难梭菌感染率的影响：来自试点纵向欧洲艰难梭菌感染的结果诊断监测研究（LuCID）
8. Clostridium difficile Infections: Diagnosis, Treatment, and Prevention. Clinician Research Summary. [R] . 2011

机译：艰难梭菌感染：诊断，治疗和预防。临床医师研究摘要。

Diagnosis of Clostridium difficile Infections in Children

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