Incidence of Extended-Spectrum-β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates That Test Susceptible to Cephalosporins and Aztreonam by the Revised CLSI Breakpoints

Carla S. McWilliams; Susan Condon; Rebecca M. Schwartz; Christine C. Ginocchio

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Incidence of Extended-Spectrum-β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates That Test Susceptible to Cephalosporins and Aztreonam by the Revised CLSI Breakpoints

机译：经修订的CLSI断点测试对头孢菌素和氨曲南敏感的产大范围β-内酰胺酶的大肠杆菌和肺炎克雷伯菌的发生率

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The incidence of aztreonam and cephalosporin susceptibility, determined using the revised CLSI breakpoints, for extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae isolates was evaluated. Our analysis showed that results for aztreonam and/or ≥1 cephalosporin were reported as susceptible or intermediate for 89.2% of ESBL-producing E coli isolates (569/638 isolates) and 67.7% of ESBL-producing K. pneumoniae isolates (155/229 isolates).

机译：评估了使用修订后的CLSI断裂点确定的广谱β-内酰胺酶（ESBL）产大肠埃希菌和肺炎克雷伯菌分离株氨曲南和头孢菌素敏感性的发生率。我们的分析表明，据报道，氨曲南和/或≥1头孢菌素的结果对89.2％的ESBL产大肠杆菌分离株（569/638分离株）和67.7％的ESBL产K敏感或中等肺炎链球菌分离株（155/229分离株）。 展开▼

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《Journal of Clinical Microbiology》 |2014年第7期|共3页

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Carla S. McWilliams; Susan Condon; Rebecca M. Schwartz; Christine C. Ginocchio;
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中图分类医学微生物学（病原细菌学、病原微生物学）;

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1. Comparison of CLSI 2009, CLSI 2010 and EUCAST cephalosporin clinical breakpoints in recent clinical isolates of Escherichia coli, Klebsiella pneumoniae and Klebsiella oxytoca from the SMART Global Surveillance Study [J] . Hawser S.P., Badal R.E., Bouchillon S.K., International journal of antimicrobial agents . 2010,第3期

机译：来自SMART全球监测研究的大肠杆菌，肺炎克雷伯菌和产氧克雷伯菌最近临床分离株中CLSI 2009，CLSI 2010和EUCAST头孢菌素临床断点的比较

2. Comparison of CLSI 2009, CLSI 2010 and EUCAST cephalosporin clinical breakpoints in recent clinical isolates of Escherichia coli, Klebsiella pneumoniae and Klebsiella oxytoca from the SMART Global Surveillance Study [J] . Hawser S.P., Badal R.E., Bouchillon S.K., International journal of antimicrobial agents . 2010,第Suppla3期

机译：来自SMART全球监测研究的大肠杆菌，肺炎克雷伯菌和产氧克雷伯菌最近临床分离株中CLSI 2009，CLSI 2010和EUCAST头孢菌素临床断点的比较

3. High frequency of β-lactam susceptibility in CTX-M-type extended-spectrum-β-lactamase-producing Klebsiella pneumoniae, Escherichia coli and Proteus mirabilis according to the new CLSI recommendations [J] . Katia Ruschel Pilger de Oliveira, Ana Lucia Peixoto de Freitas, Denise Maria Cunha Willers, Journal of Antimicrobial Chemotherapy . 2010,第11期

机译：根据新的CLSI建议，在生产CTX-M型超广谱β-内酰胺酶的肺炎克雷伯菌，大肠埃希菌和奇异变形杆菌中，β-内酰胺敏感性较高

4. Optimization of expression conditions of dhaT gene from Klebsiella pneumoniae in Escherichia coli using uniform design [C] . China-Japan-Korea Joint Symposium on Enzyme Engineering . 2004

机译：均匀设计法优化肺炎克雷伯菌dhaT基因在大肠杆菌中的表达条件。

5. Lipopolysaccharide inner core oligosaccharide biosynthesis and outer membrane stability in Escherichia coli and Klebsiella pneumoniae. [D] . Frirdich, Emilisa. 2005

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6. Incidence of Extended-Spectrum-β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates That Test Susceptible to Cephalosporins and Aztreonam by the Revised CLSI Breakpoints [O] . Carla S. McWilliams, Susan Condon, Rebecca M. Schwartz, 2014

机译：经修订的CLSI断点测试对头孢菌素和氨曲南敏感的产大范围β-内酰胺酶的大肠杆菌和肺炎克雷伯菌的发生率

7. Incidence of Extended-Spectrum- -Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates That Test Susceptible to Cephalosporins and Aztreonam by the Revised CLSI Breakpoints [O] . C. S. McWilliams, S. Condon, R. M. Schwartz, 2014

机译：延长光谱 - 即酰胺酶的大肠杆菌和Klebsiella肺炎的发病率和Klebsiella肺炎群分离物，该试验易受经修订的CLSI断裂点对头孢菌素和阿兹特隆的影响

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2. 重症监护病房患者医院感染产β-内酰胺酶和头孢菌素酶的肺炎克雷伯菌耐药性及基因型研究 [J] . 刘立新 ,章华萍 . 疾病监测 . 2013,第010期

3. 产超广谱β-内酰胺酶及头孢菌素酶肺炎克雷伯菌耐药现状及防治 [J] . 丘岳 ,蒋霞 ,黄健 . 广西医科大学学报 . 2013,第005期

4. 同时产DHA-1型头孢菌素酶和SHV-12型超广谱β内酰胺酶的肺炎克雷伯菌 [J] . 管希周 ,刘又宁 ,罗燕萍 . 中华结核和呼吸杂志 . 2005,第007期

5. 2010年CLSI三代头孢菌素折点改变对我国大肠埃希菌和肺炎克雷伯菌及奇异变形杆菌药物敏感性结果解释的评估 [J] . 刘文静 ,季萍 ,刘蓬蓬 . 中华检验医学杂志 . 2010,第010期

6. CLSI第三代头孢菌素新旧折点对判定肺炎克雷伯菌药物敏感性及产ESBLs菌株分布的影响 [C] . 许伟伟 ,江洋 ,熊自忠 . 中华医学会第三届感染与抗微生物治疗论坛、第九届全国感染性疾病及抗微生物化疗学术会议、第一届上海国际临床微生物及抗微生物化疗学术会议 . 2011

7. 发酵重组大肠杆菌产（+）γ-内酰胺酶及酶的固定化研究 [A] . 李伟 . 2015

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机译：抗菌成分（蛋白质）和蛋白质作为针对铜绿假单胞菌，肺炎克雷伯菌，大肠埃希氏菌，肠炎沙门氏菌和葡萄球菌溶血性葡萄球菌的抗菌剂的用途

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Incidence of Extended-Spectrum-β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates That Test Susceptible to Cephalosporins and Aztreonam by the Revised CLSI Breakpoints

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