Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient

Joseph Canterino; Alberto Paniz-Mondolfi; Barbara A. Brown-Elliott; Wilson Vientos; Ravikiran Vasireddy; Richard J. Wallace; Sheldon Campbell

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Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient

机译：固体器官移植后患者的Nonocardia thailandica肺部Nocardiosis

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Nocardia thailandica is a rare pathogen related to Nocardia asteroides, Nocardia neocaledoniensis, and Nocardia caishijiensis that, since its original description in 2004, has only been reported to cause wound and ocular infections in humans. We report a case of pulmonary nocardiosis caused by Nocardia thailandica in a 66-year-old solid organ transplant patient from Connecticut, which was identified at the molecular taxonomic level by secA1 analysis, 16S rRNA gene sequencing, and matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS). To our knowledge, this is the first reported case of N. thailandica in the United States and the first report of pulmonary infection by this pathogen in the literature.

机译：泰国诺卡氏菌是与诺卡氏小行星，新诺卡氏犬和菜氏诺卡氏菌有关的罕见病原体，自2004年首次描述以来，仅被报道会引起人类伤口和眼部感染。我们报道了一例由康涅狄格州的66岁实体器官移植患者中的泰国诺卡氏菌引起的肺部心肌病，该患者通过 secA1 分析，16S rRNA基因测序和基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）。据我们所知，这是美国首次报道的泰国猪笼草病例，也是文献中首次报道这种病原菌引起的肺部感染。 展开▼

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《Journal of Clinical Microbiology》 |2015年第11期|共5页

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Joseph Canterino; Alberto Paniz-Mondolfi; Barbara A. Brown-Elliott; Wilson Vientos; Ravikiran Vasireddy; Richard J. Wallace; Sheldon Campbell;
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中图分类医学微生物学（病原细菌学、病原微生物学）;

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1. Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient [J] . Joseph Canterino, Alberto Paniz-Mondolfi, Barbara A. Brown-Elliott, Journal of Clinical Microbiology . 2015,第11期

机译：固体器官移植后患者的Nonocardia thailandica肺部Nocardiosis

2. In vitro activity of multiple antibiotic combinations against Nocardia: relationship with a short-term treatment strategy in heart transplant recipients with pulmonary nocardiosis. [J] . Tripodi MF, Durante Mangoni E, Fortunato R, Transplant infectious disease: an official journal of the Transplantation Society . 2011,第4期

机译：多种抗生素组合对诺卡氏菌的体外活性：与肺移植性心脏病的心脏移植接受者的短期治疗策略相关。

3. Case report: pulmonary nocardiosis caused by Nocardia exalbida in an immunocompetent patient [J] . Abe Seitaro, Tanabe Yoshinari, Ota Takeshi, BMC Infectious Diseases . 2021,第1期

机译：病例报告：由诺卡迪亚Exalbida在免疫活性患者中引起的肺伤害

4. HIGH-DOSE MELPHALAN CHEMOTHERAPY WITH AUTOLOGOUS STEM CELL TRANSPLANTATION IN 65 PATIENTS WITH AL AMYLOIDOSIS: ORGAN PROGRESSION CAN BE DELAYED IN PATIENTS REACHING COMPLETE REMISSION [C] . SO Schonland, J.B Dengler, M Hundemer, International Symposium on Amyloidosis . 2008

机译：在65例Al淀粉样蛋白患者中，具有自体蛋白化疗的高剂量蛋白化疗：器官进展可以延迟达到完全缓解的患者

5. Adjusting to life as an organ transplant recipient: A clinician's guide for the use of Therapeutic Assessment in the treatment of adolescent organ transplant recipients [D] . Weed, Valerie 2014

机译：适应器官移植接受者的生活：治疗评估在青春期器官移植接受者治疗中的临床医生指南

6. Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient [O] . Joseph Canterino, Alberto Paniz-Mondolfi, Barbara A. Brown-Elliott, 2015

机译：固体器官移植后患者的Nonocardia thailandica肺部Nocardiosis

7. Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient [O] . Joseph Canterino, Alberto Paniz-Mondolfi, Barbara A. Brown-Elliott, 2015

机译：在固体器官移植患者的Nocardia泰国肺病虫病

1. 实体器官移植后肺部病毒感染的影像学进展 [J] . 董莘 . 中华临床医师杂志（电子版） . 2013,第002期

2. 器官移植后肺部感染影像相关问题 [J] . 蒋涛 ,刘士远 ,肖湘生 . 中国医学计算机成像杂志 . 2010,第005期

3. 实体器官移植后非感染性肺部并发症的诊断与治疗 [J] . 王东 ,张波 . 国际呼吸杂志 . 2006,第002期

4. 实体器官移植后肺部感染的诊断及治疗进展 [J] . 张英为 ,蔡后荣 . 国际呼吸杂志 . 2005,第011期

5. 支气管肺泡灌洗治疗肺切除后呼衰患者肺部严重感染rn支气管肺泡灌洗治疗肺切除后呼衰患者肺部严重感染 [J] . 许栋生 ,邹卫 ,叶猛 . 江苏医药 . 2001,第003期

6. 器官移植后肺部感染 [C] . 童朝晖 . 第六届中国呼吸医师论坛 . 2007

7. miRNAs在器官移植后免疫抑制患者HCMV感染中的致病机制研究 [A] . 路艳芳 . 2018

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3. isolated antibody, tumor necrosis factor 25 receptor-specific toxin (tnfr25), method for activating tumor necrosis factor 25 receptor (tnfr25), method for inhibiting tumor necrosis factor 25 receptor (tnfr25) signaling in a cell , antitumor vaccine, method for immunizing a patient against tumor, method for treating cancer in a patient, method for treating and / or preventing intestinal inflammation, therapeutic composition for facilitating an organ transplant, method for transplanting tissue from a donor to a host, method for inhibiting clonal expression of a cognate cd8 t cell population, method for treating and / or preventing pulmonary inflammation, isolated tnfr25 antagonist, composition and expression vector [P] . 外国专利： BRPI0617057A2 . 2011-07-12

机译：分离的抗体，肿瘤坏死因子25受体特异性毒素（tnfr25），激活肿瘤坏死因子25受体（tnfr25）的方法，抑制细胞中肿瘤坏死因子25受体（tnfr25）信号传导的方法，抗肿瘤疫苗，抗肿瘤患者，治疗患者癌症的方法，治疗和/或预防肠道炎症的方法，促进器官移植的治疗组合物，将组织从供体移植到宿主的方法，抑制同源cd8克隆表达的方法t细胞群体，治疗和/或预防肺部炎症的方法，分离的tnfr25拮抗剂，组合物和表达载体

4. PREPARATION FOR THE TREATMENT OF OTHERS TISSUE, PROCESS FOR THE PREPARATION OF EX-VIVO OTHERS TISSUE BEFORE TRANSPLANTATION OR THEIR USE AS A CURING MATERIAL, PROCESS FOR THE TREATMENT OF A PATIENT, AND, PROCESS FOR PERFORMING ALLOGENIC OR XENOGENIC ORGAN ORGAN TRANSPLANTS A HUMAN PATIENT, OR TO PROVIDE ALLOGENIC OR XENOGENIC DRESSING TO THIS PATIENT [P] . 外国专利： BR9007769A . 1992-08-11

机译：处理其他组织的准备工作，在移植之前或在将其用作治疗材料的体外处理其他组织的准备工作，处理患者的过程以及进行同种异体或异种器官或人类器官移植的过程或为该患者提供同种或异种治疗

5. ISOLATED ANTIBODY, NUCLEIC ACID, VECTOR, ISOLATED CELL, METHODS FOR PRODUCTING AN ANTIBODY, TO TREAT DISEASE OR DISORDER, TO TREAT OR PREVENT REJECTION IN A HUMAN TRANSPLANT PATIENT TO BE TURNED TO HUMAN, TO EXHAUST T CELLS EXPRESSING ICOS IN A HUMAN PATIENT, TO BREAK THE GERMINAL CENTER ARCHITECTURE IN A PRIMARY SECONDARY LYMPHID ORGAN, TO DEPLETE GERMAN CENTRAL LYMPHIDE ORGAN B CELLS WITH A PRIMATE BULTA IN CURRENT CLASSES IN A PRIMATE, AND, PHARMACEUTICAL COMPOSITION. [P] . 外国专利： BRPI0811466A2 . 2014-10-14

机译：分离的抗体，核酸，矢量，分离的细胞，生产抗体，治疗或预防人类移植患者的抗体，治疗疾病或疾病的方法，转化为人类，排泄在人体内表达ICOS的细胞破坏初级二级淋巴器官中的生殖器中心体系结构，以主要的和药物组成的当前类消耗具有主要胸腺的德语中央淋巴结有机器官B细胞。

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Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient

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