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Cost-Effective Respiratory Virus Testing

机译：具有成本效益的呼吸道病毒测试

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The timely and accurate diagnosis of respiratory virus infections has the potential to optimize downstream (posttesting) use of limited health care resources, including antibiotics, antivirals, ancillary testing, and inpatient and emergency department beds. ABSTRACT The timely and accurate diagnosis of respiratory virus infections has the potential to optimize downstream (posttesting) use of limited health care resources, including antibiotics, antivirals, ancillary testing, and inpatient and emergency department beds. Cost-effective algorithms for respiratory virus testing must take into consideration numerous factors, including which patients should be tested, what testing should be performed (for example, antigen testing versus reverse transcription-PCR testing or influenza A/B testing versus testing with a comprehensive respiratory virus panel), and the turnaround time necessary to achieve the desired posttesting outcomes. Despite the clinical impact of respiratory virus infections, the cost-effectiveness of respiratory virus testing is incompletely understood. In this article, we review the literature pertaining to the cost-effectiveness of respiratory virus testing in pediatric and adult patient populations, in emergency department, outpatient, and inpatient clinical settings. Furthermore, we consider the cost-effectiveness of a variety of testing methods, including rapid antigen tests, direct fluorescent antibody assays, and nucleic acid amplification tests.
机译：及时准确地诊断呼吸道病毒感染可能会优化下游有限的医疗资源（测试后），包括抗生素，抗病毒药，辅助检查以及住院和急诊病床。摘要及时，准确地诊断呼吸道病毒感染可能会优化下游有限医疗资源的使用（后检测），包括抗生素，抗病毒药，辅助检测以及住院和急诊病床。具有成本效益的呼吸道病毒检测算法必须考虑众多因素，包括应检测哪些患者，应进行哪些检测（例如，抗原检测与逆转录PCR检测或流感A / B检测与综合检测呼吸道病毒小组），以及达到理想的后期测试结果所需的周转时间。尽管呼吸道病毒感染有临床影响，但呼吸道病毒检测的成本效益尚不完全清楚。在本文中，我们回顾了有关在儿科和成年患者人群，急诊科，门诊和住院临床环境中进行呼吸道病毒检测的成本效益的文献。此外，我们考虑了多种测试方法的成本效益，其中包括快速抗原测试，直接荧光抗体测定和核酸扩增测试。

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