• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Assessment Of Polyalthia Longifolia Var. Pendula For Hypoglycemic And Antihyperglycemic Activity
【24h】

Assessment Of Polyalthia Longifolia Var. Pendula For Hypoglycemic And Antihyperglycemic Activity

机译：紫花苜蓿的评估摆锤具有降血糖和降血糖作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The hypoglycemic and antihyperglycemic activity of various solvent extracts of Polyalthia longifolia var. pendula leaf extracts was evaluated in alloxan induced experimental diabetes in rats. Diabetes was induced using 180 mg/kg i.p. of alloxan consecutively two times at an interval of 24 h. The test drugs were administered for 7 days. On 8th day various biochemical parameters like serum cholesterol, serum urea, serum creatinine, serum triglyceride, total serum protein, serum alkaline phosphatase, blood glucose and glycogen from liver were estimated. Polyalthia longifolia extracts and powder produced glucose lowering activity. However, the extracts did not modify any of the biochemical parameter significantly. Hence the extracts and crude powder are devoid of anti-diabetic properties, but has gross glucose lowering properties. The presence of anti-hyperglycemic effect against sucrose loading induced hyperglycemia is a significant finding. Now-a-days, it is considered that this effect is most important property in a drug used in diabetes treatment.
机译：紫花苜蓿各种溶剂提取物的降血糖和降血糖活性。在四氧嘧啶诱导的大鼠实验性糖尿病中评估了摆叶提取物。使用180 mg / kg i.p.诱导糖尿病。每隔24小时连续两次注射四氧嘧啶。将测试药物给药7天。在第8天，估算了各种生化参数，例如血清胆固醇，血清尿素，血清肌酐，血清甘油三酸酯，总血清蛋白，血清碱性磷酸酶，血糖和肝糖原。长寿花提取物和粉末可降低葡萄糖的活性。但是，提取物并未显着改变任何生化参数。因此，提取物和粗粉没有抗糖尿病特性，但是具有降低总葡萄糖的特性。对蔗糖负荷引起的高血糖症的抗降血糖作用的存在是一个重要发现。如今，人们认为这种作用是用于糖尿病治疗的药物中最重要的特性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号