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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Carcinoid of the Caecum with Osseousand Soft Tissue Metastases:A Rare Case Report
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Carcinoid of the Caecum with Osseousand Soft Tissue Metastases:A Rare Case Report

机译:盲肠类骨质伴软组织转移的罕见病例报告

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Background: The carcinoid tumour arises from the enterochromaffin cells of Kulchitsky at the base of the crypts of Leiberkuhn. Gastrointestinal (GI) carcinoids account for 95 % of all the carcinoids and caecal carcinoids account for 5 % of all the carcinoids. They remain silent and asymptomatic for years and many a times, are diagnosed intraoperatively, endoscopically or during autopsy, based on their histopathological findings. Malignant carcinoids metastasise to the liver and the lymph nodes, while bone and soft tissue metastasis have rarely been reported. We present here, a rare case of caecal carcinoid with bone and soft tissue metastasis.Case Report: A 47 year old female was admitted with pain in the abdomen in our hospital, 3 years back. Colonoscopy showed caecal pathology, for which resection and anastomosis was done. Her post operative histopathology revealed carcinoidof the caecum which invaded the subserosa with lymph node metastasis. She received adjuvant chemotherapy and presented to the OPD 3 years later, with swellings over the medial end of the right clavicle, the anterior chest wall and the node on the right side of the neck. FNAC from all these sites revealed metastatic carcinoid. She was treated with chemotherapy and palliative radiotherapy and has been asymptomatic for the past two years.Conclusion: Carcinoids are slow growing, indolent tumours and they may remain asymptomatic for years. Malignant carcinoids rarely metastasise to the bone and soft tissues. The present report adds to the literature, an interesting case of caecal carcinoid with osseous and soft tissue metastasis, besides highlighting the importance of histopathology in its diagnosis, as well as the role of chemotherapy and palliative radiotherapy in controlling the symptoms.
机译:背景:类癌是由Leiberkuhn隐窝底部的Kulchitsky肠嗜铬细胞引起的。胃肠(GI)类癌占所有类癌的95%,而盲肠类癌占所有类癌的5%。根据他们的组织病理学发现,他们在手术中,内窥镜检查或尸检期间被诊断多年无声无症状。恶性类癌转移到肝脏和淋巴结,而骨和软组织转移很少见。病例报告:3年前,我院一名47岁的女性因腹部疼痛入院。结肠镜检查显示盲肠病理,为此进行了切除和吻合。她的术后组织病理学显示盲肠类癌侵犯了浆膜下淋巴结转移。她接受了辅助化疗,并于3年后出现在OPD中,右锁骨内侧末端,前胸壁和颈部右侧结节肿胀。所有这些部位的FNAC均显示出转移性类癌。她接受了化学疗法和姑息放疗的治疗,并且在过去的两年中一直无症状。结论:类癌生长缓慢,肿瘤顽固,并且可能多年没有症状。恶性类癌很少转移至骨骼和软组织。本报告增加了文献报道,一个有趣的盲肠类癌伴骨和软组织转移的病例,除了强调组织病理学在其诊断中的重要性,以及化学疗法和姑息放疗在控制症状中的作用。

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