...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Phenotypic Characterization and Antifungal Susceptibility Pattern to Fluconazole in Candida species Isolated from Vulvovaginal Candidiasis in a Tertiary Care Hospital
【24h】

Phenotypic Characterization and Antifungal Susceptibility Pattern to Fluconazole in Candida species Isolated from Vulvovaginal Candidiasis in a Tertiary Care Hospital

机译：三级保健医院念珠菌外阴念珠菌中念珠菌中氟康唑的表型特征和抗真菌药性模式

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Vaginal candidiasis is a common gynecological finding among women worldwide. This study was carried out to determine the prevalence of vulvovaginal candidiasis (VVC) along with speciation of Candida with special reference to its antifungal susceptibility pattern to fluconazole and also to evaluate the risk factors responsible for VVC in patients attending our tertiary care hospital in Puducherry, India.Materials and Methods: This study was carried out in the tertiary care hospital in Puducherry during the period of August 2010 to September 2012.The study group consisted of 180 women between the age group of 15 to 56 years with the complaints of excessive vaginal discharge, pruritis and pain. Materials used for this study consisted of high vaginal swabs from patients with relevant history, attending Obstetrics & Gynecology department. High vaginal swabs were subjected to direct 10% KOH wet mount microscopy, Gram stain, culture onto Sabouraud?s dextrose agar (SDA) & 5% sheep blood agar and susceptibility testing to fluconazole was performed using E-test.Results: Candida was isolated in 40(22.2 %) women & these consisted of C. albicans 26 (65%), C. glabrata 9(22.5%), C.tropicalis 3(7.5%) & C. parapsilosis 2(5%). Susceptibility test carried out on the 40 isolates revealed that 35 (87.5%) Candida isolates were sensitive to fluconazole, 3 (7.5%) were moderately sensitive and 2 (2.5%) were resistant. Thirty one percent patients had itching as the presenting complaints followed by vaginal discharge (29.4%).Conclusion: The high frequency with which C. albicans was recovered in our study and its susceptibility to fluconazole supports the continued use of azole agents for empirical therapy of uncomplicated candidal vulvovaginitis in the community.
机译：背景：阴道念珠菌病是全球女性普遍的妇科发现。进行这项研究是为了确定念珠菌外阴阴道炎（VVC）以及念珠菌的种类，并特别参考其对氟康唑的抗真菌药性模式，并评估在我们位于Puducherry的三级护理医院就诊的患者中导致VVC的危险因素，印度。材料与方法：本研究于2010年8月至2012年9月在Puducherry的三级护理医院进行，研究组由180名年龄在15至56岁之间的女性组成，她们抱怨阴道过度阴道。分泌物，瘙痒和疼痛。这项研究使用的材料包括来自有相关病史的高阴道拭子，就读于妇产科。高阴道拭子直接用10％KOH湿法显微镜检查，革兰氏染色，在Sabouraud的葡萄糖琼脂（SDA）和5％羊血琼脂上培养，并使用E检验对氟康唑进行药敏试验。结果：分离出念珠菌40名（22.2％）妇女中，其中包括白色念珠菌26（65％），光滑念珠菌9（22.5％），热带念珠菌3（7.5％）和副腿念珠菌2（5％）。对40株分离株进行的药敏试验表明，有35株（87.5％）念珠菌对氟康唑敏感，其中3株（7.5％）为中度敏感，2株（2.5％）有耐药性。 31％的患者因主诉而出现瘙痒，随后出现白带（29.4％）。结论：本研究中白念珠菌的康复频率很高，并且对氟康唑的敏感性支持继续使用吡咯类药物进行经验性治疗。社区中未发生复杂的念珠菌性阴道炎。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号