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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Temporal Dimension in Reference StandardMisclassification ? A Concept Note
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Temporal Dimension in Reference StandardMisclassification ? A Concept Note

机译：参考标准中的时间维度分类错误？概念说明

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摘要

In situations of diagnostic tests studies where the gold standard(GS) test is not absolutely perfect, validity measures of index tests vary in subgroups with varying disease prevalence. This is called reference standard misclassification. Although this is widely known, little is explained about the variations in the performance of index tests when the validity of the GS test itself varies with the time duration of illness. This article attempts to expand the concept of reference standard misclassification specifically on the effect of time dependence of diagnostic tests. A brief literature review is also presented which documents the existent knowledge among researchers about the concept and the methods they usually employ to adjust. A list of solutions which can address the issue has also been discussed to enable researchers to design and analyse diagnostic test studies in better ways.
机译：在诊断测试研究中，黄金标准（GS）测试不是绝对完美的情况下，指数测试的有效性指标随疾病患病率的不同而有所不同。这称为参考标准分类错误。尽管这是众所周知的，但当GS测试本身的有效性随疾病持续时间而变化时，对于索引测试性能的变化的解释很少。本文尝试扩展参考标准错误分类的概念，特别是针对诊断测试的时间依赖性的影响。还提供了简短的文献综述，该文献记录了研究人员中有关该概念及其通常用于调整的方法的现有知识。还讨论了可以解决该问题的解决方案列表，以使研究人员能够更好地设计和分析诊断测试研究。

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