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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Sagittal Abdominal Diameter to Measure Visceral Adipose Tissue in Overweight or Obese Adolescent Children and Its Role as A Marker of Insulin Resistance
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Sagittal Abdominal Diameter to Measure Visceral Adipose Tissue in Overweight or Obese Adolescent Children and Its Role as A Marker of Insulin Resistance

机译：矢状腹径测量超重或肥胖青少年儿童的内脏脂肪组织及其作为胰岛素抵抗的标志物的作用

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Background: Measurement of sagittal abdominal diameter using a revalidated caliper is simple, inexpensive, non-invasive method. It strongly correlates with insulin resistance and can be used as a surrogate marker to predict risk for Type II Diabetes Mellitus. Aim: To assess visceral abdominal fat by measuring sagittal abdominal diameter using sliding calipers and to predict insulin resistance in obese or overweight adolescent children. S tudy design: Explorative study for Paediatric age group among over weight and obese children aged 10-18 years in urban population in a Tertiary Care Centre. Materials and Methods: Paediatric population satisfying ADA guidelines for diagnosis of prediabetes were included in the study. Anthropometric measurements with SAD were recorded. Blood was collected to investigate for prediabetes and insulin resistance using HOMA-IR. Results: Out of 924 subjects who gave assent to participate in study 108 fulfilled ADA criteria. 33 subjects who didn?t come for the follow up were excluded. Out of 75 subjects 12 were detected to have insulin resistance (16%) and 63 were normal (84%). Pearson?s partial correlation of HOMA-IR and OGTT with SAD has demonstrated it to be better correlation with Insulin Resistance (IR) than other anthropometric measurements. Fasting Glucose correlated better with Waist Hip Circumference. Conclusion: Insulin Resistance was diagnosed in 16% of the population and these had high levels of insulin resistance. SAD in relation to glucose metabolism, had a better correlation with OGTT followed by HOMA-IR and fasting Insulin. SAD with anthropometric measurements had better correlation all the parameters other than Waist Circumference, which had negative correlation. SAD can be used in evaluation of obese or overweight children for evaluation.
机译：背景：使用重新验证的卡尺测量矢状腹径是一种简单，廉价，无创的方法。它与胰岛素抵抗密切相关，可以用作预测II型糖尿病风险的替代指标。目的：通过使用游标卡尺测量矢状腹径来评估内脏腹部脂肪，并预测肥胖或超重青少年儿童的胰岛素抵抗。研究设计：在三级医疗中心，对城市人口中10-18岁的超重和肥胖儿童的小儿年龄组进行探索性研究。材料和方法：本研究包括符合ADA准则的糖尿病前期诊断的儿科人群。记录了SAD的人体测量结果。使用HOMA-IR收集血液以调查糖尿病前期和胰岛素抵抗。结果：同意参加研究108的924名受试者符合ADA标准。不参加随访的33名受试者被排除在外。在75名受试者中，有12名具有胰岛素抵抗（16％），而63名是正常（84％）。皮尔逊将HOMA-IR和OGTT与SAD的部分相关性证明，与其他人体测量法相比，它与胰岛素抵抗（IR）的相关性更好。空腹血糖与腰围臀围相关性更好。结论：在16％的人群中诊断出胰岛素抵抗，这些人群的胰岛素抵抗水平很高。与葡萄糖代谢有关的SAD与OGTT，HOMA-IR和空腹胰岛素的相关性更好。人体测量的SAD与腰围以外的所有参数具有更好的相关性，而腰围为负相关。 SAD可用于评估肥胖或超重儿童以进行评估。

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