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首页> 外文期刊>Journal of Clinical and Diagnostic Research >The Bacteriology of Diabetic Foot Ulcers, with a Special Reference to Multidrug Resistant Strains
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The Bacteriology of Diabetic Foot Ulcers, with a Special Reference to Multidrug Resistant Strains

机译：糖尿病足溃疡的细菌学，特别涉及耐多药菌株

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Introduction: A diabetic foot infection is one of the most feared complications of Diabetes mellitus. Many studies have reported on the bacteriology of Diabetic Foot Infections (DFIs) over the past 25 years, but the results have been varied and often contradictory.Aims and Objectives: This study was carried out to determine the bacterial profiles of infected ulcers and the antibiotic resistance pattern of the isolates.Materials and Methods: Samples were collected from 50 patients with diabetic foot ulcers by using sterile swabs and they were processed.Results: A total of 75 bacterial isolates were obtained from 50 patients with diabetic foot ulcers. The age group of these patients ranged from 35 to 80 years and the maximum number of patients was in the age group of 60 to 65 years. Gram negative bacilli were more prevalent (65.1%) than gram positive cocci (34.9%). The commonest isolate was Pseudomonas spp (16%), followed by Escherichia coli (14.6%) and Staphylococcus aureus (13.3%).The antibiotic sensivity profiles of the bacteria were also studied. 37.5% of the gram negative bacilli were ESBL producers and 31% were carbapenemase producers.Conclusion: This study showed a preponderance of gram negative bacilli among the isolates from the diabetic foot ulcers. Knowledge on the antibiotic sensitivity pattern of the isolates will be helpful in determining the drugs for the empirical treatment of diabetic ulcers.
机译：简介：糖尿病足感染是糖尿病最令人担忧的并发症之一。在过去的25年中，许多研究都报道了糖尿病足感染（DFI）的细菌学，但是结果却千差万别，而且常常是矛盾的。分离物的耐药模式。材料与方法：用无菌棉签从50例糖尿病足溃疡患者中取样并进行处理。结果：从50例糖尿病足溃疡患者中共获得75株细菌。这些患者的年龄组为35至80岁，最大患者数为60至65岁。革兰氏阴性菌比革兰氏阳性球菌（34.9％）更为普遍（65.1％）。最常见的分离株是假单胞菌（Pseudomonas spp）（16％），其次是大肠杆菌（14.6％）和金黄色葡萄球菌（13.3％）。还研究了该细菌的抗生素敏感性分布。革兰氏阴性杆菌中37.5％是ESBL产生者，而31％是碳青霉烯酶产生者。结论：本研究显示在糖尿病足溃疡中分离出的革兰氏阴性菌占优势。有关分离物抗生素敏感性模式的知识将有助于确定用于糖尿病性溃疡经验治疗的药物。

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