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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Correlation Between Collagen Fibers and Radiographic Patterns of Keratocystic Odontogenic Tumour
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Correlation Between Collagen Fibers and Radiographic Patterns of Keratocystic Odontogenic Tumour

机译：胶原纤维与角化囊性牙源性肿瘤的放射学特征之间的相关性

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Background: WHO has recently renamed odontogenic keratocyst as keratocystic odontogenic tumour (KCOT) depending on its tumour like behaviour.Aim: To quantitate and qualitate different types of collagen fibers in KCOT using picrosirius red stain under polarising microscopy and to correlate with different radiographic patterns of KCOT to elucidate its biological behaviour in order to determine whether all KCOTs behave like a tumour.Materials and Methods: Sixty histopathologically confirmed cases of KCOT were selected and stained histochemically using picrosirius red and examined under polarising microscope to evaluate colour of collagen fibers in the wall. Radiographic analysis of all the cases were also carried out and correlated with type of collagen of fibers.Results: Greenish yellow collagen fibers were present statistically significantly more in multilocular KCOT and KCOT with multiple radiolucencies (both syndromic and non-syndromic) as compare to unilocular whereas orange red were significantly more in unilocular variety. Syndromic variety showed significantly higher number of greenish yellow collagen fibers than non-syndromic variety.Conclusion: Quality, organization and packing of collagen fibers of unilocular type is different than other radiographic patterns which accounts for difference in biological behaviour of these lesion, so we conclude that aggressive treatment should be reserved for selected cases.
机译：背景：世界卫生组织（WHO）最近根据其像肿瘤的行为将牙源性角化囊改名为角质囊性牙源性肿瘤（KCOT）。材料和方法：选择60例经组织病理学确诊的KCOT病例，并用picrosirius红对组织进行化学染色，并在偏光显微镜下进行检查，以评估其壁中胶原纤维的颜色。 。结果：与单眼相比，多眼KCOT和KCOT具有多种放射线透过率（有症状和无症状）的黄绿色胶原纤维在统计学上显着多于黄色胶原纤维。而橙红色在单眼品种中明显更多。结论：单眼型胶原纤维的质量，组织和堆积与其他射线照相方式不同，这说明这些病变的生物学行为不同，因此我们得出结论：应该为某些情况保留积极治疗。

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