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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Efficacy of Four Fluoride Mouth Rinses on Streptococcus mutans in High Caries Risk Children ? A Randomized Controlled Trial
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Efficacy of Four Fluoride Mouth Rinses on Streptococcus mutans in High Caries Risk Children ? A Randomized Controlled Trial

机译：四种氟漱口液对高龋风险儿童变形链球菌的疗效？随机对照试验

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Introduction: Dental caries has been traditionally described as a multifactorial disease that involves the interaction of various factors like host, agent, substrate and time. Landmark studies have established the fact that Mutans Streptococci are the primary etiologic agents of dental caries. The prevention of dental caries by fluoride supplements in various vehicles, such as water and toothpaste, constitutes one of the most successful prevention measures.Aim: The aim of the present study was to compare the clinical efficacy of four fluoride mouth rinses on Streptococcus mutans in high caries risk children and also to check the efficacy of the ingredient Triclosan which is present in two of the four mouth rinses.Materials and Methods: The study is double blinded, consisting of 1000 children in age group 6-14yrs who were screened from residential schools. Of the total, 200 children were categorized as high caries risk group based on caries risk assessment tool form given by American Association of Pediatric Dentistry (AAPD) guidelines 2011. Prior to the study, salivary samples were collected and sent for microbial analysis to estimate Streptococcus mutans counts. Out of 200 salivary samples, 132 showed 106CFU of Streptococcus mutans and these children were included in the study. The 132 children from each group received the assigned mouth wash for 14 consecutive days. On 15th day the salivary samples were collected and sent for microbial analysis and the obtained results were subjected to statistical analysis.Results: All the mouth washes showed a significant reduction in Colony Forming Units (CFU) counts of Streptococcus mutans. Among the four groups Group D (S flo) showed greater percentage reduction of Streptococcus mutans followed by Group A (Act), B (Kidodent) and C (Zerocary). There was no stastically significance reduction of Streptococcus mutans among the Triclosan containing and non containing groups.Conclusion: The mean pre rinse CFU was significantly higher than post rinse CFU for all the study groups, suggesting that all the four mouth rinses were effective in decreasing the levels of Streptococcus mutans in the saliva. Both the Triclosan containing and non Triclosan groups showed the same amount of CFU count reduction.
机译：简介：龋齿在传统上被描述为一种多因素疾病，涉及宿主，病原体，基质和时间等各种因素的相互作用。具有里程碑意义的研究确定了事实，即Mutans链球菌是龋齿的主要病因。在各种媒介物（例如水和牙膏）中添加氟化物来预防龋齿是最成功的预防措施之一。目的：本研究的目的是比较四种氟化物漱口水对变形链球菌的临床疗效。高龋风险的儿童，并还要检查四次漱口液中有两种的三氯生成分的功效。材料与方法：这项研究是双盲的，包括1000例6-14岁年龄段的儿童，这些儿童是从居住区进行筛查的学校。根据美国小儿牙科协会（AAPD）指南2011年提供的龋齿风险评估工具表，将200名儿童归为高龋齿风险组。在研究之前，收集唾液样本并送去进行微生物分析以估计链球菌。变形计数。在200份唾液样本中，有132份显示106CFU变形链球菌，这些儿童被纳入研究。每组的132名儿童连续14天接受指定的漱口水。在第15天，收集唾液样品并进行微生物分析，并对获得的结果进行统计学分析。结果：所有漱口液均显示变形链球菌的菌落形成单位（CFU）计数显着减少。在四组中，D组（S flo）显示出变形链球菌降低的百分比更大，其次是A组（Act），B组（Kidodent）和C组（Zerocary）。结论：所有研究组的平均漱口前CFU均高于漱口后CFU，这表明四次漱口液均能有效降低三氯生的变形链球菌含量。唾液中变形链球菌的水平。含有三氯生的组和不含三氯生的组均显示出相同量的CFU计数减少。

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