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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Morphometric Analysis of Peripapillary Thickness in Hypertensives and Normotensives using Optical Coherence Tomography (OCT)
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Morphometric Analysis of Peripapillary Thickness in Hypertensives and Normotensives using Optical Coherence Tomography (OCT)

机译：使用光学相干断层扫描（OCT）进行高血压和血压正常者的视乳头厚度的形态分析

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Introduction: Hypotension following antihypertensive treatment is associated with retinal nerve fibre loss. There are studies that have reported the changes in RNFL in hypertensives. Aim: To compare the Retinal Nerve Fibre Layer (RNFL) thickness using Optical Coherence Tomography (OCT) in hypertensive and normotensive individuals. Materials and Methods: The cross-sectional study was conducted from October 2012 to September 2014 to compare the RNFL thickness using SD OCT in hypertensive {no other ocular or systemic co-morbidity, vision better or equal to 6/9 (n=30)} and normotensive (n=30) individuals. Results: Statistically significant RNFL loss was detected in hypertensives (98.31 ± 7.01) when compared to the normotensives (102.51 ± 8.72) p=0.001. Conclusion: Significant loss of RNFL in hypertensives point towards the altered autoregulation and warrants larger studies to assess the clinical relevance.
机译：简介：降压治疗后的低血压与视网膜神经纤维丢失有关。有研究报告了高血压中RNFL的变化。目的：使用光学相干断层扫描（OCT）比较高血压和血压正常个体的视网膜神经纤维层（RNFL）厚度。材料和方法：横断面研究于2012年10月至2014年9月进行，比较了使用SD OCT治疗高血压患者（无其他眼部或全身合并症，视力更好或等于6/9（n = 30））的RNFL厚度。 }和血压正常的（n = 30）个人。结果：与正常血压（102.51±8.72）相比，高血压（98.31±7.01）中检测到具有统计学意义的RNFL损失p = 0.001。结论：高血压中RNFL的显着丧失表明自身调节改变，需要进行更大的研究以评估其临床相关性。

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