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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Clinicomorphological Study of Leiomyoma Associated Endometrial Changes in Correlation with LMP: In a Tertiary Care Hospital in Rural Tamil Nadu
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Clinicomorphological Study of Leiomyoma Associated Endometrial Changes in Correlation with LMP: In a Tertiary Care Hospital in Rural Tamil Nadu

机译:子宫肌瘤与LMP相关的子宫内膜变化的临床形态学研究:在泰米尔纳德邦农村三级医院

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Leiomyomas are benign smooth muscle tumors. They are the single most common cause for hysterectomy in the reproductive and peri-menopausal age group associated with abnormal uterine bleeding. There are certain endometrial changes with leiomoyomas due to hormonal and mechanical influences of the leiomyomas.Aim: To study the incidence of leiomyomas of uterus in a rural area of Tamil Nadu and the endometrial changes associated with it correlating it to the LMP, in hysterectomy specimens.Materials and Methods: This is a retrospective study of three hundred thirty one patients who underwent hysterectomy for uterine leiomyoma between 2013 and 2015, histopathological analysis of the cases for endometrial changes was done.Results: A total of 331 hysterectomy specimens done for leiomyomas were studied. The most common age group was observed as 41-50 years (56.50%). Multiparous women (94.86%) are more commonly affected. Menorrhagia was the most common symptom seen in 46.53%. Majority of the cases had a single leiomyoma (59.82%). The most common location was intramural (49.85%). The most common degenerative change associated with a leiomyoma was hyaline change (23.87%). The most common type of endometrium was proliferative endometrium observed in 44.41%. The percentage of mailignacy associated with a leiomyoma was 0.60%.Conclusion: Leiomyomas are the most common causes for hysterectomy. The associated endometrial change is proliferative in nature suggesting the role of harmones such as oestrogen and progesterone on the leiomyoma and simultaneously on the corresponding endometrium.
机译:平滑肌瘤是良性平滑肌肿瘤。它们是与子宫异常出血相关的生殖和绝经年龄组子宫切除的最常见原因。目的:研究泰米尔纳德邦农村地区子宫平滑肌瘤的发生率以及与子宫内膜异位症相关的子宫内膜变化与子宫内膜异位症的关系, 材料与方法:这是一项回顾性研究,对2013年至2015年间接受子宫子宫肌瘤子宫切除术的331例患者进行了子宫内膜变化病例的组织病理学分析。结果:A总共研究了331例子宫肌瘤子宫切除术标本。观察到最常见的年龄组为41-50岁(56.50%)。产妇(94.86%)受感染的可能性更大。月经过多是最常见的症状,占46.53%。大多数病例有单个平滑肌瘤(59.82%)。最常见的位置是壁内(49.85%)。与平滑肌瘤相关的最常见的退行性改变是透明质酸改变(23.87%)。子宫内膜最常见的类型是增生性子宫内膜,占44.41%。与平滑肌瘤相关的mailignacy百分比为0.60%。结论:平滑肌瘤是子宫切除术的最常见原因。相关的子宫内膜改变本质上是增殖性的,表明诸如雌激素和孕酮的调和子在平滑肌瘤上以及同时在相应的子宫内膜上起着作用。

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