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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Rare Case of Paranasal Sinus Schwannoma with Intracranial Extension
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A Rare Case of Paranasal Sinus Schwannoma with Intracranial Extension

机译:罕见的鼻旁窦神经鞘瘤伴颅内延伸的病例

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Paranasal sinus schwannomas are uncommon and account for less than 4% of head and neck schwannomas. Intracranialextension and aggressive behaviour are very rarely observed in these tumours leading to misdiagnosis of a malignant neoplasm.Here, we report a case of a 35-year-old male with complaint of proptosis. MRI showed a tumour in the region of ethmoid sinuswith expansion into anterior cranial fossa. Microscopy revealed a biphasic tumour with compact and loose areas. Tumour wascomposed of spindle cells with wavy nuclei, showing focal palisading and a strong immunoreactivity for S100. MIB-1 index wasaround 1%. A diagnosis of Schwannoma was favoured based on histology and immunohistochemistry.
机译:鼻旁窦神经鞘瘤不常见,占头颈部神经鞘瘤的不到4%。在这些肿瘤中极少出现颅内屈伸和侵略性行为,导致对恶性肿瘤的误诊。在此,我们报道一例35岁男性患有眼球突出症。 MRI显示筛窦区域有肿瘤,并扩展为前颅窝。显微镜检查显示为双相性肿瘤,具有致密和疏松的区域。肿瘤由具有波状核的梭形细胞组成,显示出局灶性麻痹和对S100的强免疫反应性。 MIB-1指数约为1%。基于组织学和免疫组化的诊断,对神经鞘瘤的诊断受到青睐。

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