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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Hospital Based Serosurveillance Study of Dengue Infection in Jaipur (Rajasthan) , India
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A Hospital Based Serosurveillance Study of Dengue Infection in Jaipur (Rajasthan) , India

机译：印度斋浦尔（拉贾斯坦邦）的一家基于医院的登革热感染血清监测研究

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Background: Dengue has been known to be endemic in India for over two centuries. There is a need to assess the magnitude of dengue virus establishment in the state of Rajasthan. A surveillance study was conducted to analyze dengue seropositivity among patients with clinical suspicion of dengue fever like illness, who presented to or were admitted at a tertiary care private hospital at Jaipur.Methods: Serum samples from 2169 suspected dengue cases (1356 males and 813 females) were received in the Serology lab over the four year study period (2008-2011). The samples were subjected to a rapid immuno-chromatography assay with differential detection of IgM and IgG antibodies. A primary dengue infection was defined by a positive IgM band and a negative IgG band, whereas a secondary infection was defined by a positive Ig G band with or without an IgM band.Result: Among the 2169 patients who were screened; 18.99% (412) were dengue specific IgM positive cases. 64. 49% (1399) cases were negative for dengue specific antibodies, 5.67% (123) were primary dengue cases, and 23.51% (510) were total secondary dengue cases. During the study period, the Dengue IgM seropositivity was highest in the year 2009 and was lowest in the year 2011. Most of the cases occurred in the post-monsoon season, with a peak in the month of October, each year.Conclusion: A detailed and continuous epidemiological surveillance is required, for monitoring the incrusion and spread of dengue viruses. This will help in undertaking and implementing effective control and management strategies.
机译：背景：登革热在印度已经流行了两个多世纪。有必要评估拉贾斯坦邦登革热病毒的建立规模。进行了一项监测研究，以分析在临床上怀疑患有登革热（例如疾病）并在斋浦尔一家三级私立医院就诊或入院的登革热血清阳性的患者。方法：从2169例疑似登革热病例中抽取血清（男性1356例，女性813例）在为期四年的研究期间（2008-2011）在血清学实验室接受了）。对样品进行快速免疫色谱分析，并对IgM和IgG抗体进行差异检测。初次登革热感染由IgM阳性带和IgG阴性带定义，继发感染由有或没有IgM带阳性的Ig G带定义。登革热特异性I​​gM阳性病例为18.99％（412）。 64.登革热特异性抗体阴性的占49％（1399），原发登革热病例占5.67％（123），总继发登革热病例占23.51％（510）。在研究期间，登革热IgM血清阳性在2009年最高，在2011年最低。大多数病例发生在季风后季节，每年10月达到峰值。需要进行详细，连续的流行病学监测，以监测登革热病毒的扩散和传播。这将有助于采取和实施有效的控制和管理策略。

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