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首页> 外文期刊>Journal of Clinical and Diagnostic Research >An Invitro Comparative Evaluation of Compressive Strength and Antibacterial Activity of Conventional GIC and Hydroxyapatite Reinforced GIC in Different Storage Media
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An Invitro Comparative Evaluation of Compressive Strength and Antibacterial Activity of Conventional GIC and Hydroxyapatite Reinforced GIC in Different Storage Media

机译：常规GIC和羟基磷灰石增强GIC在不同存储介质中的抗压强度和抗菌活性的体外比较评估

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Background: GIC is the most commonly used restorative material in pediatric dentistry since it has got various advantages like fluoride release, anticariogenic property and chemical adhesion to tooth but a major disadvantage is its contraindication in posterior teeth because of poor mechanical properties. Aim: The purpose of this study is a modest attempt to explore the influence of the addition of 8% hydroxyapatite to conventional GIC on its compressive strength when immersed in different storage media and antibacterial activity. Materials and Methods: One hundred and twenty six pellets of the specific dimension of 6 x 4 mm were prepared and divided into 6 groups and were immersed in deionized water, artificial saliva, lactic acid solution respectively for three hours everyday over 30 days test period. The compressive strength was measured by using a universal testing machine (AG-50kNG) at cross head of 1mm2/min and strength was determined after 1 day, 7 days, 30 days respectively and the antibacterial activity evaluated against Streptococcus mutans strain in brain heart infusion broth using serial dilution method. Statistical Analysis: Group wise comparisons were made by one-way ANOVA followed by post-hoc Tukey?s test, Intergroup comparison was done with Mann-Whitney test. R esults: GIC+HAp showed significantly greater antibacterial activity against Streptococcus mutans when compared to GIC group. There was no statistically significant change in the compressive strength among the groups except for group 3 and group 6 when immersed in lactic acid had shown significant difference at the end of 24 hours. Conclusion: The addition of 8% hydroxyapatite to GIC showed marked increased in the antibacterial activity of the conventional GIC against caries initiating organism without much increase in the compressive strength of the GIC when immersed in the different storage media.
机译：背景：GIC是儿科牙科中最常用的修复材料，因为它具有氟化物释放，防龋齿特性和对牙齿的化学粘合等各种优点，但主要缺点是由于机械性能较差而在后牙禁忌使用。目的：本研究的目的是进行适度尝试，以探讨向传统GIC中添加8％羟基磷灰石时，将其浸入不同的存储介质中时其抗压强度和抗菌活性的影响。材料与方法：制备特定尺寸为6 x 4 mm的126个小丸，分为6组，分别在30天的测试期内每天分别浸入去离子水，人造唾液，乳酸溶液中3小时。用万能试验机（AG-50kNG）以1mm 2 / min的十字头测量抗压强度，并分别在1天，7天，30天后测定强度，并评价脑心输液中对变形链球菌菌株的抗菌活性。肉汤使用系列稀释法。统计分析：采用单因素方差分析，事后Tukey检验进行分组比较，组间比较采用Mann-Whitney检验进行。结果：与GIC组相比，GIC + HAp对变形链球菌显示出明显更高的抗菌活性。除第3组和第6组外，当浸入乳酸中时，各组之间的抗压强度在统计学上无显着变化，在24小时末显示出显着差异。结论：向GIC中添加8％羟基磷灰石表明，传统GIC浸入不同存储介质中时，其对龋齿引发生物的抗菌活性显着提高，而GIC的抗压强度却没有太大提高。

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