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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Acute Transfusion Reactionsin Intensive Care Unit:A Retrospective Study
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Acute Transfusion Reactionsin Intensive Care Unit:A Retrospective Study

机译：重症监护室急性输血反应的回顾性研究

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Background: Blood transfusion is a frequent and integral part of critical care. Although life saving, it can occasionally be unsafe and result in a spectrum of adverse events. Acute transfusion reactions (ATRs) are probably under diagnosed in critically ill patients due to confusion of the symptoms with the underlying disease.Aim: To analyze the incidence and spectrum of ATRs occuring in critically ill patients.Materials and Methods: This was a retrospective review conducted from 1st April 2011 till 31st March 2013. The ATRs related to the administration of blood components in the patients admitted in various Intensive Care Units (ICUs) were recorded, analyzed and classified on the basis of their clinical features and laboratory tests.Results: During the study period 98651 blood components were issued. Out of these 21971 were issued to various ICUs. A total of 225 transfusion reactions were reported from the various critical care departments during this period. The most frequent were Febrile Non Hemolytic Transfusion Reactions (FNHTR) 136 (60.4%), allergic reactions 70 (31.2%), hemolytic reactions 1(0.4%) and non specific reactions 18 (8%). The incidence of ATRs in our study was found to be 1.09% in adult ICUs and 0.36% in pediatric ICUs.Conclusions: Blood transfusion is a vital therapeutic procedure with a potential risk to already critical patients. So a strict vigilance has to be kept and each transfusion has to be monitored carefully with prompt recognition and treatment of ATRs. A rational use of these products considering their deleterious effects can decrease transfusion related morbidity and mortality in the critically ill patients.
机译：背景：输血是重症监护的常见组成部分。尽管可以挽救生命，但有时还是不安全的，并导致一系列不良事件。急性输血反应（ATR）可能由于症状与潜在疾病的混淆而被诊断为诊断目的，分析重症患者发生的ATR的发生率和频谱材料和方法：回顾性回顾于2011年4月1日至2013年3月31日进行。对根据重症监护病房（ICU）住院患者的血液成分管理相关的ATR进行了记录，分析和分类，并根据其临床特征和实验室测试进行了分类。结果：在研究期间，发出了98651份血液成分。在这21971年中，发行给各种ICU。在此期间，各个重症监护部门共报告了225次输血反应。最常见的是高热非溶血性输血反应（FNHTR）136（60.4％），变态反应70（31.2％），溶血反应1（0.4％）和非特异性反应18（8％）。在我们的研究中，ATR的发生率在成人ICU中为1.09％，在小儿ICU中为0.36％。结论：输血是至关重要的治疗方法，对已经危重的患者具有潜在的风险。因此，必须保持高度的警惕，每次输血都必须通过及时识别和治疗ATR进行仔细监测。考虑到它们的有害作用，合理使用这些产品可以降低重症患者输血相关的发病率和死亡率。

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