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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Impact of Amitryptiline on Migraine Disability Assessment Score
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Impact of Amitryptiline on Migraine Disability Assessment Score

机译：阿米替林对偏头痛残疾评估评分的影响

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Aim: Migraine headache is a common disorder, several drugs have been tried as a prophylaxis to reduce the attacks of headache. Aim of this study is to see the impact of amitriptyline on quality of life in migraneurs using Migraine Disability Assessment Score.Materials and Methods: In this study 300 patients of either gender who required prophylaxis for migraine without aura were selected. The patients were of the age group 18-60 years. The MIDAS questionnaire was administered to patients before starting treatment and again after 45 days prophylaxis. The improvement was noted. Statistical Analysis: It is a prospective study where the severity of symptoms and ?quality of life? in patients is assessed before and after treatment using mean, frequency, standard deviation and paired?t? test.Results: A total of 300 patients were subjected to migraine prophylaxis with amiptriptyline. The study showed female preponderance. The mean MIDAS score before and after treatment with amitriptyline was 11.6 and 9.4 respectively. The student?t? test showed p-value of <0.005 which was significant.Conclusion: Migraine prophylaxis with amitriptyline for a period of 45 days decreased the severity of symptoms and also reduction in days of migraine attacks. However the long term effects on quality of life could not be assessed. The study needs to be conducted in a large scale to evaluate the consistency and accuracy of the test.
机译：目的：偏头痛是一种常见的疾病，已经尝试了多种药物来减轻头痛的发作。这项研究的目的是使用偏头痛残障评估评分来观察阿米替林对偏头痛患者生活质量的影响。材料与方法：在这项研究中，选择了300名需要预防无先兆偏头痛的男女患者。患者年龄在18-60岁。在开始治疗前和预防45天后再次对患者进行MIDAS问卷调查。注意到了改进。统计分析：这是一项前瞻性研究，其中症状的严重程度和“生活质量”如何？使用均值，频率，标准差和配对t？来评估治疗前后的患者结果：总共300例患者接受了阿米替林预防偏头痛。研究显示女性占优势。阿米替林治疗前后的平均MIDAS评分分别为11.6和9.4。学生吗？试验显示p值<0.005，这是显着的。结论：阿米替林预防偏头痛45天可降低症状的严重程度，并减少偏头痛发作的天数。但是，无法评估对生活质量的长期影响。该研究需要大规模进行，以评估测试的一致性和准确性。

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