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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Role of Gender and Serum Immunoglobulin E (IGE) levels on Severity of Migraine
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Role of Gender and Serum Immunoglobulin E (IGE) levels on Severity of Migraine

机译：性别和血清免疫球蛋白E（IGE）水平对偏头痛严重程度的作用

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Aim: Migraine headache is a common disorders. Several studies have reported that migraine headache is more common in patients with allergy. Aim of this study is to determine if the allergic sensitization is associated with the prevalence, frequency, and disability of migraine headaches.Materials and Methods: The study was conducted during the period August 2013. During this period 100 patients of either gender who were diagnosed with migraine were selected and total serum Immunoglobulin E (IGE) levels were estimated. Prevalence of migraine headache and degree of allergic sensitization was estimated in these patients. Severity of migraine was assessed using the MIDAS score.Statistical Analysis: Descriptive tables were generated showing the demographic and clinical characteristics of participants stratified by age and sex. Differences between subject groups were assessed by chi-square test. Correlation between severity of migraine and IgE levels was calculated using Pearson correlation.Results: A total of 100 patients with migraine who presented to the outpatient department where studied. Prevalence of migraine was found to be higher in females compared to males. At the younger age group IgE levels were higher. Patients with higher levels of IgE had more severe headaches compared to those with lower levels of IgE. Patients with higher levels of IgE required a longer duration of treatment compared to those with lower levels of IgE.Conclusion: Prevalence of migraine is high among females. Younger age and female sex are other contributory factors as prevalence of migraine is higher in these groups. Degree of allergic sensitisation determines the severity and frequency of headaches in those whom allergic rhinitis is a risk factor as evidenced by higher levels of IgE.
机译：目的：偏头痛是一种常见的疾病。几项研究报告说，偏头痛在变态反应患者中更为常见。这项研究的目的是确定过敏性致敏症是否与偏头痛的患病率，频率和残疾有关。材料与方法：这项研究于2013年8月进行。在此期间，被诊断为100名男女患者选择偏头痛患者并评估血清总免疫球蛋白E（IGE）水平。在这些患者中估计偏头痛的患病率和过敏致敏程度。使用MIDAS评分评估偏头痛的严重程度。统计分析：生成描述性表格，显示按年龄和性别分层的参与者的人口统计学和临床​​特征。通过卡方检验评估受试者组之间的差异。使用皮尔森相关性计算偏头痛严重程度与IgE水平之间的相关性。结果：共有100名偏头痛患者出现在所研究的门诊部。发现女性偏头痛患病率高于男性。在较年轻的年龄组中，IgE水平较高。与较低水平的IgE相比，较高水平的IgE的患者头痛更为严重。 IgE水平较高的患者与IgE水平较低的患者相比需要更长的治疗时间。结论：偏头痛的患病率在女性中较高。年龄偏低和女性性别是其他因素，因为这些组的偏头痛患病率较高。过敏性过敏的程度决定了过敏性鼻炎是危险因素的那些人的头痛的严重程度和发生频率，如较高的IgE水平所证明的。

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