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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Rare Case of Multiple Myeloma with Biclonal Gammopathy
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A Rare Case of Multiple Myeloma with Biclonal Gammopathy

机译:多发性骨髓瘤双克隆性乳腺病罕见病例

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Multiple myeloma is a debilitating malignancy arising from plasma cells. These malignant plasma cells called myeloma cells proliferate and infiltrate the bone marrow. The disease is characterized by the presence of a monoclonal protein in plasma and/or the urine. In this report, we present a case of biclonal multiple myeloma which showed two M bands on serum protein electrophoresis. The patient had elevated serum IgA and IgG levels. To reveal the nature of M bands or clonality, serum Immunofixation study was performed which revealed IgA with Lambda and IgG with Kappa light chains. Such pattern is very rare if we consider the various immunofixation patterns observed in different gammopathies.
机译:多发性骨髓瘤是浆细胞引起的衰弱性恶性肿瘤。这些称为骨髓瘤细胞的恶性浆细胞增殖并浸润骨髓。该疾病的特征在于血浆和/或尿液中存在单克隆蛋白。在本报告中,我们介绍了一例双侧性多发性骨髓瘤,该病例在血清蛋白电泳中显示两个M条带。该患者的血清IgA和IgG水平升高。为了揭示M条带或克隆性的性质,进行了血清免疫固定研究,该研究揭示了具有λ的IgA和具有κ轻链的IgG。如果我们考虑在不同配子病中观察到的各种免疫固定模式,这种模式非常罕见。

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