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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Comparison of Alkalinized and Non-Alkalinized Lignocaine inthe Brachial Plexus Block
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Comparison of Alkalinized and Non-Alkalinized Lignocaine inthe Brachial Plexus Block

机译：臂丛神经阻滞中碱化和非碱化的利多卡因的比较

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Introduction: Interruption of pain is central to the anaesthetic practice. Regional anaesthesia is one of the widely practiced ways for mitigating surgical pain. Many long acting local anaesthetics have been tried, viz.. bupivacaine, ropivacaine but they are limited by the drawbacks of delayed onset, the varying quality of the blockades and their unpredictable duration of action. The alkalinization of lignocaine has been shown to fasten the onset, potency and the duration of the block. Type of study: Randomized single blind clinical trial. Materials and Methods: After obtaining the institutional ethical committee clearance and their written informed consent, fifty patients who were aged between 25-50 yrs, of either sex, who belonged to ASA grade 1 and 2, who were posted for elective/ emergency surgery of the upper limb were enrolled for the study. Group 1 received 30ml of 1.5% lignocaine with adrenaline and Group 2 received 30 ml of 1.5% alkalinized lignocaine with adrenaline. A supra-clavicular block by a classical approach was made and the degree of the blockade was graded. The results were tabulated and analyzed by using appropriate statistical tests. Conclusion: Alkalinization of lignocaine offers an earlier onset and it provides a good intensity and adequate depth and a satisfactory distribution of the regional block.
机译：简介：中断疼痛是麻醉实践的核心。区域麻醉是减轻手术疼痛的广泛实践方法之一。已经尝试了许多长效局麻药，例如布比卡因，罗哌卡因，但是它们受到以下因素的限制：起效延迟，封锁的质量不同以及作用时间不可预测。木质素卡因的碱化作用已显示出可加快起效作用，效力和持续时间。研究类型：随机单盲临床试验。资料和方法：在获得机构伦理委员会的批准并获得他们的书面知情同意后，年龄在25至50岁之间的50名患者（分别属于ASA 1和2级）属于ASA等级1和2，并接受了以下手术：招募上肢进行研究。第一组接受30ml 1.5％的利多卡因和肾上腺素，第2组接受30ml 1.5％碱化的木利卡因和肾上腺素。通过经典方法进行了锁骨上阻滞，并对阻滞的程度进行了分级。将结果制成表格并通过适当的统计检验进行分析。结论：利多卡因的碱化作用起效较早，并具有良好的强度和足够的深度以及令人满意的局部区域分布。

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