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首页> 外文期刊>Journal of Clinical and Diagnostic Research >The Microbial Colonization Profile of Respiratory Devices and the Significance of the Role of Disinfection: A Blinded Study
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The Microbial Colonization Profile of Respiratory Devices and the Significance of the Role of Disinfection: A Blinded Study

机译：呼吸装置的微生物定殖概况和消毒作用的意义：一项盲研究

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Introduction: Approximately 10-40% of all the nosocomial infections are pulmonary, which lead to grave complications. Elderly, debilitated, or critically ill patients are at a high risk. The respiratory care equipments which include ventilators, humidifiers, nebulizers may have been identified as the potential vehicles which cause major nosocomial infections if they are colonized by fungi or bacteria.Aim: To determine the rate of colonization by bacteria and fungi of the oxygen humidifier chambers of the portable cylinders and central lines at our hospital. The Hudson?s chambers of nebulizers were also studied for the same.Methods: Swab samples were obtained from the equipments by using sterile cotton swabs on a tuesday, as these chambers were usually cleaned on every Saturday. Spot samples were taken from the ICUs, wards, the casualty and OPDs on a single day. Air samples were also obtained on the same day to determine whether the fungal spore load in the inhaled room air was normal or high. We performed a disinfection with 70% ethanol after cleaning these devices.Results: 53/70 (75.71%) samples showed fungal growth; out of which, 23/33 (69.70%) were from the ICU, 24/30(80%) were from the wards and 6/7 (85.71%) were from the OPDs. 23/30 (76.66%) swabs from the central line humidifiers, 18/23(78.26%) swabs from the O2 cylinder humidifiers and 8/17 (47.5%) swabs from the nebulizers grew bacteria. Of the total 61(87.14%) bacterial isolates, 42(68.85%) were gram negative bacteria and 19(31.14%) were gram positive cocci. Out of the 42 gram negative bacteria, 17 were multi-drug resistant like ESBL producers ie. Pseudomonas spp. (6) Acinetobacter spp.(4), Klebseilla pneumoniae (4), E.coli (2) and Stenotrophomonas maltophila (1). Our findings (before disinfection) showed that the colonization rate for fungi was 75% and that for bacteria, it was 87%. After the 70% ethanol disinfection and strict compliance with the hand hygiene, the colonization rates reduced significantly. The fungal colonization rate was reduced and only 15% fungi grew after the disinfection, while only 12% bacterial colonization rate was found.Conclusion: This study indicates a potential in-hospital source of allergens and infections. The oxygen and nebulizer chambers need to be cleaned more frequently with disinfectants, to control the possible nosocomial infections.
机译：简介：所有医院感染中约有10-40％是肺部感染，这会导致严重的并发症。老年人，虚弱或重症患者处于高风险中。如果呼吸防护设备（包括呼吸机，加湿器，雾化器）被真菌或细菌定殖，则可能被认为是引起重大医院感染的潜在媒介物。目的：确定氧气加湿器室中细菌和真菌的定殖率我们医院的便携式气瓶和中心线。方法：在星期二使用无菌棉签从设备上获得拭子样品，因为通常在每个星期六清洁这些腔室。当天从ICU，病房，伤亡人员和OPD中抽取了现场样本。当天还获得了空气样本，以确定吸入的室内空气中的真菌孢子负荷是正常还是较高。清洁这些设备后，我们用70％的乙醇进行了消毒。结果：53/70（75.71％）的样品显示出真菌的生长;其中，ICU的23/33（69.70％），病房的24/30（80％）和OPD的6/7（85.71％）。来自中线加湿器的23/30（76.66％）拭子，来自O2钢瓶加湿器的18/23（78.26％）拭子和来自雾化器的8/17（47.5％）拭子使细菌滋生。在总共61种（87.14％）细菌分离物中，有42种（68.85％）是革兰氏阴性细菌，有19种（31.14％）是革兰氏阳性球菌。在42克阴性细菌中，有17种具有多重耐药性，例如ESBL生产商。假单胞菌（6）不动杆菌属（4），肺炎克雷伯菌（4），大肠杆菌（2）和嗜麦芽嗜单胞菌（1）。我们的发现（消毒前）表明，真菌的定殖率为75％，细菌的定殖率为87％。在用70％的乙醇消毒并严格遵守手部卫生规定后，定植率显着降低。消毒后真菌定植率降低，仅生长15％的真菌，而细菌定植率仅为12％。结论：该研究表明医院内可能的过敏原和感染源。氧气和雾化室需要使用消毒剂更频繁地清洁，以控制可能的医院感染。

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