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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Dexamethasone as An Additive to Bupivacaine in Fascia Lliaca Compartment Block: A Prospective, Randomized and Double Blind Study
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Dexamethasone as An Additive to Bupivacaine in Fascia Lliaca Compartment Block: A Prospective, Randomized and Double Blind Study

机译：地塞米松作为筋膜筋膜隔室中布比卡因的添加剂：一项前瞻性，随机和双盲研究

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Background: Patients with fracture femur experience severe pain on movement during positioning for spinal anaesthesia. Fascia Iliaca Compartment Block (FICB) has been used effectively for providing analgesia during positioning of the patient for spinal anaesthesia.Aim: To test the hypothesis that, adding dexamethasone would significantly prolong the duration of Bupivacaine in FICB.Materials and Methods: Sixty patients aged 18 to 80 years posted for ORIF (Open Reduction and Internal Fixation) of fracture femur were included to receive FICB. This was a prospective, randomized, double blind study done at tertiary medical college hospital. Thirty patients received 38ml of 0.25 % bupivacaine with 2ml saline and another 30 patients received 38ml of 0.25 % bupivacaine with 2ml dexamethasone (8mg). Thirty minutes after FICB, patient satisfaction during positioning for spinal anesthesia was recorded. In the post-operative period, duration of analgesia and the total doses of rescue analgesics were recorded in both the groups.Results: Patients who received Bupivacaine with dexamethasone had significant prolongation of analgesia and required fewer doses of rescue analgesics as compared to patients who received Bupivacaine alone for FICB. However the onset of analgesia, VAS scores and patient satisfaction during positioning for spinal anaesthesia were similar in both groups.Conclusion: Our study shows that adding Dexamethasone (8mg) to Bupivacaine for FICB significantly prolonged the duration of block and decreased the requirement of rescue analgesics as compared to patients who received Bupivacaine alone. FICB is relatively easy and safe to perform. In our study we did not encounter any complication while doing the procedures and also by adding dexamethasone.
机译：背景：股骨骨折患者在进行脊髓麻醉的定位过程中会遭受剧烈的运动疼痛。 Fascia Iliaca隔室阻滞（FICB）已被有效地用于在脊柱麻醉患者定位过程中提供镇痛作用。接受18至80年因股骨骨折的ORIF（开放复位和内固定）而接受FICB治疗。这是在三级医学院医院进行的一项前瞻性，随机，双盲研究。 30例患者接受38ml 0.25％布比卡因和2ml生理盐水，另外30例患者接受38ml 0.25％布比卡因和2ml地塞米松（8mg）。 FICB后30分钟，记录了在进行脊髓麻醉定位期间的患者满意度。结果：接受布比卡因联合地塞米松治疗的患者术后镇痛时间明显延长，需要的抢救镇痛药剂量较术前减少。单独的布比卡因用于FICB。然而，两组麻醉的镇痛效果，VAS评分和患者对脊髓麻醉的满意程度均相似。结论：我们的研究表明，在布比卡因中添加地塞米松（8mg）用于FICB显着延长了阻滞时间并降低了急救镇痛药的需求与仅接受布比卡因的患者相比。 FICB相对容易且安全地执行。在我们的研究中，通过添加地塞米松也没有遇到任何并发症。

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