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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Relationship of Lipid Profile and Serum Ferritin levels with Acute Myocardial Infarction
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Relationship of Lipid Profile and Serum Ferritin levels with Acute Myocardial Infarction

机译：血脂和血清铁蛋白水平与急性心肌梗死的关系

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Introduction: National Health and Nutrition Examination Survey (NHANES III), 1988-1994, first time reported a significant, positive association in iron storage and heart disease risk. Thereafter several researchers have found an association between iron overload, serum ferritin (SF) and MI. No such Indian study was available in the literature and so we decided to find out the relation of lipid profile and Serum Ferritin with myocardial infarction (MI).Materials and Methods: Fifty indian patients of AMI (study group) and fifty indian healthy volunteers (control group) were included for the present study. Lipid profile including TC, HDL-c, LDL-c, VLDL-c & TG and SF levels were estimated in all subjects.Observations and Results: Mean ± SD of TC level was 250.64 ± 25.61, of HDL-c was 36.52 ± 2.86, of LDL-c was 165.69 ± 26.80, of VLDL-c was 42.35 ± 8.53 and of TG was 211.83 ± 42.65 in study group while these values were 174.46±47.68, 43.2±12.52, 98.37±41.13, 32.88±21.45 and 164.42±107.29 respectively in control group. All the parameters were found not only raised in patients of acute myocardial infarction (AMI) but were also statistically significant when compared with control group (p=<0.01).Mean ± SD of SF levels was 268.43±30.17 ng/ml in study group and 110.96±56.5 ng/ml in control group; this level was found not only raised in patients of AMI but were also statistically significant when compared with control group (p=<0.01).Conclusion: TC, LDL-c, VLDL-c, TG and SF levels were raised in patients of AMI and found to be statistically significant; while HDL-c levels were reduced in such patients and is also statistically significant. It can be concluded that there exists an association in lipid profile and SF with AMI therefore dyslipidemia and raised SF levels are the features of AMI.
机译：简介：1988-1994年，美国国家健康与营养检查调查（NHANES III）首次报告铁存储与心脏病风险之间存在显着的正相关关系。此后，一些研究人员发现铁超负荷，血清铁蛋白（SF）和心肌梗死之间存在关联。文献中尚无此类印度研究，因此我们决定寻找脂质分布和血清铁蛋白与心肌梗死（MI）的关系。材料与方法：50例印度AMI患者（研究组）和50例印度健康志愿者（对照组）被纳入本研究。评估所有受试者的血脂水平，包括TC，HDL-c，LDL-c，VLDL-c和TG和SF水平。研究组的LDL-c为165.69±26.80，VLDL-c为42.35±8.53，TG为211.83±42.65，而这些值分别为174.46±47.68、43.2±12.52、98.37±41.13、32.88±21.45和164.42±对照组分别为107.29。发现所有参数不仅在急性心肌梗死（AMI）患者中升高，而且与对照组相比也具有统计学意义（p = <0.01）。研究组的SF水平平均值±SD为268.43±30.17 ng / ml对照组为110.96±56.5 ng / ml;发现该水平不仅在AMI患者中升高，而且与对照组相比也有统计学意义（p = <0.01）。结论：AMI患者的TC，LDL-c，VLDL-c，TG和SF水平升高并且发现具有统计学意义;而HDL-c水平在此类患者中降低，并且在统计学上也很显着。可以得出结论，血脂和SF与AMI之间存在关联，因此血脂异常和SF水平升高是AMI的特征。

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