...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Fetal Cardiodynamics by Echocardiography in Insulin Dependent Maternal Diabetes and Its Correlation with Pregnancy Outcome
【24h】

Fetal Cardiodynamics by Echocardiography in Insulin Dependent Maternal Diabetes and Its Correlation with Pregnancy Outcome

机译：超声心动图对胰岛素依赖型孕妇糖尿病的胎儿心脏动力学及其与妊娠结局的关系

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: Maternal diabetes mellitus is associated with an increased risk of fetal and neonatal morbidity and mortality. Usual screening tests have not proved to be good prognostic indicators of fetal distress. Fetal cardiodynamics is potentially a useful screening tool. Aim: To determine if cardiodynamics of the fetus differ in pregnancy with diabetes requiring insulin than those without and to determine whether cardiodynamics predict fetal and neonatal outcomes. Materials and Methods: This prospective case control study was carried out in 40 pregnant women with diabetes who required insulin for blood sugar control. Twenty uncomplicated pregnant women were taken as controls. Systolic and diastolic cardiac functions along with interventricular septal thickness were assessed at 26-28 weeks and again at 34-36 weeks of gestation in fetuses by echocardiography. Fetal and neonatal adverse outcomes were evaluated in terms of major and minor morbidity. Results: Among all parameters, E/A ratio across both mitral and tricuspid valves, myocardial performance index and cardiac output were significantly different in fetuses of diabetic mothers at both gestations. However, pulmonary vein pulsatility index and interventricular septal thickness were similar between the two groups. At 26-28 weeks of gestation myocardial performance index correlated with abnormal biophysical profile whereas cardiac output correlated with minor morbidity. At 34-36 weeks of gestation, cardiac output correlated with abnormal biophysical profile while both MPI and cardiac output correlated with minor morbidity. Conclusion: Echocardiographic parameters of fetuses of diabetic women significantly differed from those of uncomplicated non-diabetic women. However, only myocardial performance index and cardiac output correlated with adverse fetal and neonatal outcomes.
机译：简介：孕产妇糖尿病与胎儿和新生儿发病率和死亡率的增加风险有关。常规筛查测试尚未证明是胎儿窘迫的良好预后指标。胎儿心脏动力学可能是有用的筛查工具。目的：确定在需要胰岛素的糖尿病孕妇中胎儿的心脏动力学是否与没有胰岛素的胎儿心脏动力学不同，并确定心脏动力学是否可以预测胎儿和新生儿的结局。资料和方法：这项前瞻性病例对照研究是针对40名需要胰岛素控制血糖的糖尿病孕妇进行的。二十名简单的孕妇被作为对照。通过超声心动图评估胎儿在妊娠26-28周时的收缩和舒张心脏功能以及室间隔厚度，并在妊娠34-36周时再次评估。评估胎儿和新生儿不良后果的严重程度。结果：在所有参数中，两个妊娠期糖尿病母亲的胎儿二尖瓣和三尖瓣的E / A比，心肌性能指数和心输出量均存在显着差异。但是，两组之间的肺静脉搏动指数和室间隔厚度相似。妊娠26-28周时，心肌功能指数与生物物理特征异常相关，而心输出量与轻微发病率相关。在妊娠34-36周时，心输出量与异常的生物物理特征相关，而MPI和心输出量均与较小的发病率相关。结论：糖尿病女性胎儿的超声心动图参数与单纯性非糖尿病女性明显不同。但是，只有心肌功能指数和心输出量与胎儿和新生儿不良结局相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号