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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Unique Presentation of Primary Intestinal MALT Lymphoma as Multiple Lymphomatous Polyposis
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A Unique Presentation of Primary Intestinal MALT Lymphoma as Multiple Lymphomatous Polyposis

机译：原发性肠道MALT淋巴瘤作为多发性淋巴瘤性息肉病的独特表现。

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Multiple lymphomatous polyposis is considered to be a rare condition, with most of the cases being extranodal counterpart of mantle cell lymphomas. We report a rare case of multiple lymphomatous polyposis of the gastrointestinal tract in which the patient presented with abdominal pain and bloody diarrhea. Computer tomography of the abdomen showed circumferential wall thickening with intramural mass involving caecum & ascending colon with enlarged pericolonic lymph nodes. The patient underwent right hemicolectomy. Immunohistologic findings were characteristic of MALT lymphoma. Microscopic examination of polypoidal masses and mesenteric lymph nodes revealed infiltration by pleomorphic, atypical lymphoid cells which were CD20 positive and negative for CD3, CD10, Cyclin D1. Lymphoepithelial lesions were also noted. Careful endoscopic evaluation and histopathological review along with an immunohistochemical panel is extremely useful for accurately diagnosing such cases and avoiding unnecessary surgery and inappropriate therapy.
机译：多发性淋巴瘤性息肉病被认为是一种罕见的疾病，大多数病例是套细胞淋巴瘤的结外伴发。我们报道了胃肠道多发性淋巴瘤性息肉病的罕见病例，其中患者出现腹痛和血性腹泻。腹部计算机断层扫描显示，周壁增厚，壁内肿块累及盲肠和升结肠，并伴有结肠周围结肠淋巴结肿大。该患者接受了右半结肠切除术。免疫组织学发现是MALT淋巴瘤的特征。显微镜下检查息肉样肿块和肠系膜淋巴结，发现多形，非典型淋巴样细胞浸润，CD20阳性，CD3，CD10，Cyclin D1阴性。还注意到淋巴上皮病变。仔细的内窥镜评估和组织病理学检查以及免疫组织化学检查对准确诊断此类病例以及避免不必要的手术和不适当的治疗非常有用。

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