...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Role of TSH on Urinary Calcium Excretion in Post Menopausal Women of SouthIndian Population
【24h】

Role of TSH on Urinary Calcium Excretion in Post Menopausal Women of SouthIndian Population

机译：TSH在南印度人口绝经后妇女尿钙排泄中的作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Unforeseen aberrations in the hormonal status during the early postmenopausal period are responsible for several complications including osteoporosis. Thyroid Stimulating Hormone (TSH) receptors are isolated from various tissues including the bone. A low serum TSH level is known to stimulate osteoclastic activity in bone and accelerate bone resorption. Urinary calcium/creatinine (UCa/Cr) excretion ratio could be an indirect and an early indicator of loss of Bone Mineral Density (BMD). With this background, this study was planned to explore the association of serum TSH levels with the UCa/Cr excretion ratio.Methods: Forty eight women in the postmenopausal age group, with their menopausal age not more than seven years of duration were included in this study. Based on their TSH values, these subjects were divided into two groups A (TSH0.5mIU/L). Urinary calcium, UCa/Cr excretion ratio, serum phosphorous, calcium and calcium phosphorous multiplication products were estimated and compared between the two groups.Results: Twenty two (46%) women were biochemically asymptomatic hyperthyroid cases and Twenty six (54%) were euthyroid. This study documents high UCa/Cr in Group A compared to that of Group B (p<0.05). We also observed significant negative correlation of TSH with UCa/Cr excretion ratio (p=0.041, r = -0.43).Conclusion: Low serum TSH levels were associated with increased UCa/Cr excretion ratio in postmenopausal women of South Indian population.
机译：背景：绝经后早期激素状态的意外变化是造成包括骨质疏松症在内的多种并发症的原因。甲状腺刺激激素（TSH）受体是从包括骨骼在内的各种组织中分离出来的。已知血清TSH水平低会刺激骨骼中的破骨细胞活性并加速骨骼吸收。尿钙/肌酐（UCa / Cr）排泄率可能是骨矿物质密度（BMD）丧失的间接指标和早期指标。在此背景下，本研究计划探讨血清TSH水平与UCa / Cr排泄率的关系。方法：本研究纳入了绝经后年龄组的48名女性，绝经年龄不超过7年。研究。根据他们的TSH值，将这些受试者分为两组（TSH0.5mIU / L）。估算并比较了两组的尿钙，UCa / Cr排泄率，血清磷，钙和钙磷乘积。结果：生化无症状甲状腺功能亢进症患者有22例（46％），而甲状腺功能生化无症状的妇女有26例（54％）。 ％）为甲状腺功能正常。这项研究表明，与B组相比，A组的UCa / Cr高（p <0.05）。我们还观察到TSH与UCa / Cr排泄率显着负相关（p = 0.041，r = -0.43）。结论：血清TSH水平低与南印度绝经后妇女UCa / Cr排泄率增加有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号