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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Effect of Age on Response to Experimental Pain in Normal Indian Males
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Effect of Age on Response to Experimental Pain in Normal Indian Males

机译:年龄对正常印度男性对实验性疼痛反应的影响

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Background and Objectives: Response to experimental pain depends on the nature of the pain stimulus, as well as on gender, racial, cultural and socioeconomic factors. This study investigates the effect of age on pain sensitivity and cardiovascular reactivity produced by experimental pain. We have also compared the values of body mass index (BMI) and resting blood pressure of volunteers with the normal values.Materials and Methods: The study was conducted on 83 Indian males of different age groups. The volunteers were divided into 4 groups: Children, Young Adults, Middle-Aged Adults and Old Adults; and their basal parameters (BMI, resting pulse and blood pressure) were recorded. Selected volunteers were subjected to cold pressor task (CPT). Pain sensitivity (PS) (pain threshold, tolerance and pain rating on a visual analog scale) and cardiovascular reactivity (CVR) (increase in pulse and blood pressure) were recorded.Results: Many volunteers had abnormal values of BMI and resting blood pressure and had to be excluded from the study. PS and CVR between different groups were compared by oneway ANOVA. Significant differences in PS were observed, with highest pain sensitivity in Children and lowest in Old Adults. No significant differences were observed in the CVR.Conclusion: The high numbers of volunteers with abnormal basal parameters (BMI and resting blood pressure) show an urgent need to educate the general public about the dangers and risk factors of obesity and hypertension. Less exposure of children to painful encounters may be responsible for their high pain sensitivity while higher values of resting blood pressure and decreased sensitivity of the sensory systems with advancing age may be responsible for the hypoalgesia observed in old adults.
机译:背景与目的:对实验性疼痛的反应取决于疼痛刺激的性质以及性别,种族,文化和社会经济因素。这项研究调查了年龄对实验性疼痛产生的疼痛敏感性和心血管反应性的影响。我们还将志愿者的体重指数(BMI)和静息血压值与正常值进行了比较。材料与方法:该研究针对83名不同年龄段的印度男性进行。志愿者分为四组:儿童,年轻人,中年成年人和老年人。并记录其基本参数(BMI,静息脉搏和血压)。选定的志愿者接受了冷压任务(CPT)。记录疼痛敏感性(PS)(疼痛阈值,耐受性和疼痛程度,以视觉模拟量表评分)和心血管反应性(CVR)(脉搏和血压升高)。结果:许多志愿者的BMI和静息血压值均异常。必须从研究中排除。通过单因素方差分析比较不同组之间的PS和CVR。观察到PS的显着差异,儿童的疼痛敏感性最高,而成年人则最低。结论:大量具有异常基础参数(BMI和静息血压)的志愿者表明,迫切需要向公众宣传肥胖和高血压的危险和危险因素。儿童较少经历痛苦的​​经历可能是其较高的疼痛敏感性的原因,而较高的静息血压值和随着年龄的增长感觉系统的敏感性下降可能是导致老年人观察到的痛觉过敏的原因。

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