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首页> 外文期刊>Journal of Clinical and Diagnostic Research >An Increase Incidence inUric Acid Nephrolithiasis:Changing Patterns
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An Increase Incidence inUric Acid Nephrolithiasis:Changing Patterns

机译：尿酸肾结石的发病率增加：变化模式

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Introduction: Nephrolithiasis is a complex disease affecting all age groups globally. As the causative factors for nephrolithiasis rises significantly, its incidence, prevalence and recurrence continues to baffle clinicians and patients. Aim: To study the prevalence of different types of renal stones extracted by Percutaneous Nephrolithotomy (PCNL) and open surgical procedures. Materials and Methods: Renal stones from 50 patients were retrieved by Percutaneous Nephrolithotomy (PCNL), Ureterorenoscopy (URS) and open surgical techniques for qualitative tests for detection of calcium, oxalate, uric acid, phosphate, ammonium ion, carbonate, cystine and xanthine. Results: Three patients had stone removed by open surgery and rest had undergone PCNL. Nine of the stones were pure of calcium oxalate, 9 were of pure uric acid and 32 were mixed stones. Forty one stones had calcium. Among the mixed stones, oxalate was present in 25 samples (39 of total), uric acid was seen in 17 (25 of total stones), phosphate was present in 23 (23 of total) and carbonate was present in 4 stones (4 of total). Only 1 patient had triple phosphate stone. 12 were of staghorn appearance of which 6 were of struvite type, 6 were pure uric acid and remaining were mixed oxalate-phosphate stones. Conclusion: Our study, though in a small number of hospital based patients, found much higher prevalence of uric acid stones and mixed stones than reported by previous hospital based studies in north India (oxalate stones~90%, uric acid~1% and mixed stones~3%). Biochemical analysis of renal stones is warranted in all cases.
机译：简介：肾结石病是一种复杂的疾病，影响全球所有年龄段。随着肾结石病的病因明显增加，其发病率，患病率和复发继续困扰着临床医生和患者。目的：研究经皮肾镜取石术（PCNL）和开放式外科手术提取的不同类型肾结石的患病率。材料和方法：通过经皮肾镜取石术（PCNL），输尿管镜检查（URS）和开放式外科手术技术从50例患者中取出肾结石，以进行钙，草酸，尿酸，磷酸盐，铵离子，碳酸盐，胱氨酸和黄嘌呤的定性检测。结果：3例患者通过开放手术切除了结石，其余患者接受了PCNL。其中9颗是纯草酸钙，9颗是纯尿酸，32颗是混合石。四十一块石头含钙。在混合的宝石中，草酸盐存在于25个样品中（共39个），尿酸存在于17个样品中（共25个石），磷酸盐存在于23个样品中（共23个），碳酸盐存在于4个宝石中（4个宝石中）。总）。仅1例患者有三重磷酸盐结石。鹿角形外观12个，其中鸟粪型6个，纯尿酸6个，其余为草酸盐-磷酸盐混合结石。结论：我们的研究尽管在少数以医院为基础的患者中发现，尿酸结石和混合性结石的患病率比印度北部以前的医院基础研究报告的高得多（草酸盐结石〜90％，尿酸〜1％和混合性结石石头〜3％）。在所有情况下均应进行肾结石的生化分析。

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