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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Correlation of Cotinine Levels with Use of Smokeless Tobacco (Mishri) among Pregnant Women and Anthropometry of Newborn LC16-LC19
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Correlation of Cotinine Levels with Use of Smokeless Tobacco (Mishri) among Pregnant Women and Anthropometry of Newborn LC16-LC19

机译：孕妇中可替宁水平与无烟烟草使用和新生儿LC16-LC19人体测量学的相关性

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Introduction: ?Smokeless tobacco? is the term used for the tobacco that is consumed in un-burnt form and it can be used orally or nasally. Cotinine, a nicotine metabolite, is used to quantify exposure to tobacco, which readily gains access to foetal circulation. Cotinine is invariably found in coelomic, amniotic and foetal serum when maternal serum cotinine levels exceed 25ng/ml.Aim: To estimate cotinine levels among pregnant women using and not using smokeless tobacco (mishri) and to correlate cotinine level with anthropometry of newborns.Materials and Methods: A hospital based cohort study was conducted at Krishna Hospital, Karad, District Satara, Maharashtra, India. Pregnant women who were using smokeless tobacco (mishri) during pregnancy were analyzed for cotinine levels in blood by using ELISA kit tech and correlated with anthropometry of newborn babies and compared with non users of tobacco.Results: About 480 gm reduction in Birth weight and 6.5 cm reduction in birth length of babies born to mishri users compared to non users of tobacco and also cotinine levels among users were found significantly negatively correlating with anthropometric measurement of newborn babies.Conclusion: A pro-active effort is essential to educate the women about adverse effects of tobacco in general and on the intrauterine growth of the baby in particular.
机译：简介：？无烟烟草？是用于未燃烧形式消费的烟草的术语，可以口服或经鼻使用。可替宁是一种尼古丁代谢物，用于量化暴露于烟草的暴露量，烟草很容易进入胎儿循环系统。当孕妇血清可替宁水平超过25ng / ml时，会在结肠，羊水和胎儿血清中始终发现可替宁。目的：评估使用和不使用无烟烟草（密西里州）的孕妇的可替宁水平，并将可替宁水平与新生儿人体测量学相关联。方法：在印度马哈拉施特拉邦萨塔拉地区卡拉德的克里希纳医院进行了一项基于医院的队列研究。通过使用ELISA试剂盒技术对怀孕期间使用无烟烟草（mishri）的孕妇进行了血液中可替宁水平的分析，并将其与新生婴儿的人体测量学进行了比较，并与不使用烟草的人进行了比较。结果：出生体重减轻了480 gm，体重减轻了6.5克与非吸烟者相比，mishri使用者出生的婴儿的出生时长减少了cm cm，而且使用者中的可替宁水平与新生儿的人体测量值显着负相关。结论：积极主动的努力对于教育妇女有关不良反应的知识至关重要一般而言，尤其是对婴儿子宫内生长的影响。

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