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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Magnetic Resonance Imaging in Paediatric Spinal Dysraphism with Comparative Usefulness of Various Magnetic Resonance Sequences TC17-TC22
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Magnetic Resonance Imaging in Paediatric Spinal Dysraphism with Comparative Usefulness of Various Magnetic Resonance Sequences TC17-TC22

机译：儿科脊柱发育不全的磁共振成像，各种磁共振序列TC17-TC22的比较实用性

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Introduction: Spinal dysraphism occurs due to failure of fusion of parts along dorsal aspect of midline structures lying along spinal axis from skin to vertebrae and spinal cord. Congenital spinal anomalies may be minimal and asymptomatic like spinal bifida occulta, or severe with marked neurological deficits like Arnold-Chiari malformation or caudal regression syndrome. Magnetic Resonance Imaging (MRI) is the modality of choice to diagnose mild to severe spinal dysraphism.Aim: To diagnose type and extent of clinically suspected spinal anomalies by MRI scan and to compare various sequences for identifying neural tissue and fatty tissue in anomalies.Materials and Methods: Fifty paediatric patients referred with clinical suspicion of spinal anomalies for MRI scan to radiodiagnosis department and diagnosed as having spinal dysraphism on 1.5 Tesla MRI Scan, were included in this observational analytic study. Various MRI sequences were taken in multiple planes. MRI findings of spinal dysraphism were compared with detailed clinical examination or surgical findings. Osseous anomalies like spina bifida occulta were confirmed by radiographs or CT scan.Results: Out of 50 patients, type II Arnold-Chiari Malformation (34%), Spina Bifida Occulta (22%) and Diastematomyelia (18%) were common anomalies. MRI findings were well correlated with surgical findings in 20 operated cases. Nerve roots with/ without neural placode in thecal sac/outpouching were detected in combination of 3D HASTE myelographic sequence with SE/TSE T1W sequence in 24 cases; which was significantly high as compared to combinations of SE/TSE T1W sequence with TSE T2W, with STIR and with Single Shot Myelographic sequence {p-value 0.002, < 0.001 and 0.008 respectively}. Fatty component was present in dysraphism in five cases, commonly as isolated anomaly; which was detected by combination of STIR and SE/TSE T1W sequences in all five cases.Conclusion: Paediatric spinal dysraphism and associated malformations are accurately diagnosed on MRI scan. MR myelographic 3D-HASTE and STIR sequences should be a part of protocol to evaluate spinal dysraphism.
机译：简介：脊柱发育不良的发生是由于沿着从皮肤到椎骨和脊髓的脊柱轴线的中线结构的背侧部分融合失败。先天性脊柱畸形可能很小且无症状，如脊柱裂隐匿症;严重的是明显的神经系统缺陷，如Arnold-Chiari畸形或尾椎退化综合征。磁共振成像（MRI）是诊断轻度至重度脊椎功能不全的一种选择方法目的：通过MRI扫描诊断临床可疑的脊柱异常的类型和程度，并比较各种序列以识别异常中的神经组织和脂肪组织。方法：方法：本观察分析包括50例因脊柱异常而被临床怀疑为MRI扫描的放射科，并经放射诊断部门诊断为脊柱发育不良的儿童。在多个平面上拍摄了各种MRI序列。将脊椎发育不良的MRI检查结果与详细的临床检查或手术检查结果进行比较。结果：在50例患者中，II型A​​rnold-Chiari畸形（34％），脊柱双歧隐匿性（22％）和Diastematomyelia（18％）是常见异常。在20例手术病例中，MRI表现与手术表现高度相关。结合3D HASTE髓鞘造影序列和SE / TSE T1W序列，检测了在囊囊/外囊中有神经斑或无神经斑的神经根; 24例;与SE / TSE T1W序列与TSE T2W，STIR和单发性脊髓造影序列的组合相比{p值分别为0.002，<0.001和0.008}，这是非常高的。肥胖症患者中有五种成分存在脂肪，通常是孤立异常。五例均通过STIR和SE / TSE T1W序列结合检测。结论：MRI扫描可准确诊断出小儿脊柱发育不良和相关畸形。 MR脊髓3D-HASTE和STIR序列应成为评估脊柱发育不良的协议的一部分。

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