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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Rare Case of Amphotericin B Resistant Cryptococcal Meningitis in a HIV Non-reactive Immunocompetent Patient
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A Rare Case of Amphotericin B Resistant Cryptococcal Meningitis in a HIV Non-reactive Immunocompetent Patient

机译：一例罕见的两性霉素B抵抗性隐球菌性脑膜炎的艾滋病毒非反应性免疫能力强的患者

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Cryptococcus meningitis is the most common opportunistic fungal infection in immunocompromised individuals and rarely occurs in HIV non-reactive people. Fever, headache, altered sensorium and neck stiffness are the usual presenting features of meningitis and common causative agents are of viral, mycobacterial and mostly bacterial origin in an immunocompetent host. However, fungal infection should be considered amongst the differentials. Knowledge of geographical distribution and a high degree of clinical suspicion are important for an early diagnosis, institution of early treatment and ultimately preventing lethal complications. We hereby report a case of amphotericin B resistant cryptococcal meningitis in a HIV non-reactive immunocompetent individual.
机译：隐球菌脑膜炎是免疫功能低下的个体中最常见的机会性真菌感染，在非HIV感染者中很少发生。发烧，头痛，感觉觉和颈部僵硬改变是脑膜炎的常见表现，常见病原是病毒，免疫分枝杆菌和大多数细菌来源的免疫性宿主。但是，在这些差异中应考虑真菌感染。地理分布知识和高度的临床怀疑对于早期诊断，早期治疗以及最终预防致命性并发症至关重要。我们在此报告一例HIV非反应性免疫能力强的抗两性霉素B隐球菌性脑膜炎的病例。

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