...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Unusual Low-grade Occipito-temporal Ganglioglioma with Calcification
【24h】

Unusual Low-grade Occipito-temporal Ganglioglioma with Calcification

机译：异常低度枕颞神经胶质瘤伴钙化

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Ganglioglioma (GG) is a rare benign tumour which may present as focal convulsions. Complete resection of the tumour may lead to excellent recovery. The present case report describes the features of a mixed neuronal-glial tumour in a young female patient. She complained of seizures for the last several years. Magnetic Resonance Imaging (MRI) was done. T1-weighted MRI revealed a hypointense cystic lesion in right occipitotemporal region. It measured 2.8×2.2×2.2 cm. The t2-weighted image showed a hyperintense mural nodule which measured 0.4 cm approximately. The craniotomy was done and the tumour was resected. Microscopically, the tumour showed the proliferation of astrocytes and dysplastic multinuclear neuronal cells. Dysplastic cells were large with round nuclei, abnormal clustering and irregular distribution of variably sized neurons. Few multinuclear neurons were also seen. Neoplastic neuronal cells were both synaptophysin and chromogranin A positive. Proliferated astrocytes showed pilocytic features. Eosinophilic granular bodies and perivascular inflammation were also seen. The tumour was diagnosed as a case of the World Health Organisation (WHO) Grade I ganglioglioma.
机译：神经节胶质瘤（GG）是一种罕见的良性肿瘤，可能以局灶性抽搐形式出现。肿瘤的完全切除可能导致极好的恢复。本病例报告描述了年轻女性患者混合神经胶质细胞瘤的特征。她抱怨了最近几年的癫痫发作。进行了磁共振成像（MRI）。 T1加权MRI显示右枕颞区有一个低位囊性病变。尺寸为2.8×2.2×2.2cm。 t2加权图像显示高强度的壁瘤，其大小约为0.4厘米。开颅手术并切除肿瘤。在显微镜下，肿瘤显示出星形胶质细胞和发育不良的多核神经元细胞的增殖。发育异常的细胞较大，具有圆形核，异常簇聚和大小不等的神经元不规则分布。也很少见到多核神经元。肿瘤神经元细胞既是突触素又是嗜铬粒蛋白A阳性。增殖的星形胶质细胞表现出毛细血管功能。还观察到嗜酸性粒状体和血管周围炎症。该肿瘤被诊断为世界卫生组织（WHO）的I级神经节神经胶质瘤。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号