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首页> 外文期刊>Journal of Clinical and Diagnostic Research >DRESS Syndrome: An Unusual Side Effect
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DRESS Syndrome: An Unusual Side Effect

机译：DRESS综合征：异常的副作用

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摘要

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is often an overlooked entity manifesting as fatal hypersensitivity response associated with use of aromatic anti-epileptic drugs. This case report shows a case of a nine-year-old male child presenting with DRESS syndrome associated with the use of oral carbamazepine. The patient presented with high grade fever, rashes in exposed areas of face and all extremities not involving palms, soles, or oral mucosa, periorbital oedema, and cervical lymphadenopathy. Patient was managed with oral prednisolone 1 mg/kg/day. Later the drug was changed to oral Levetiracetam. Clinicians should always consider the possibility of DRESS syndrome with use of anti-epileptic drugs.
机译：嗜酸性粒细胞增多和全身症状（DRESS）综合征的药物反应通常是一个被忽视的实体，表现为与使用芳香族抗癫痫药有关的致命性超敏反应。该病例报告显示了一例9岁男孩，患有DRESS综合征，与口服卡马西平有关。该患者出现高烧，面部裸露皮疹以及所有不涉及手掌，脚底或口腔粘膜的四肢，眼眶水肿和宫颈淋巴结肿大。患者口服口服泼尼松龙1 mg / kg /天。后来该药改为口服左乙拉西坦。临床医生应始终考虑使用抗癫痫药治疗DRESS综合征的可能性。

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