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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Smear Conversion, Treatment Outcomes and the Time of Default in Registered Tuberculosis Patients on RNTCP DOTS in Puducherry, South India
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Smear Conversion, Treatment Outcomes and the Time of Default in Registered Tuberculosis Patients on RNTCP DOTS in Puducherry, South India

机译：印度南部Puducherry RNTCP DOTS登记的结核病患者的涂片转换，治疗结果和违约时间

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Background: Revised National Tuberculosis Control Programme (RNTCP) in India has achieved improved cure rates.Objectives: This study describes the achievements under RNTCP in terms of conversion rates, treatment outcomes and pattern of time of default in patients on directly observed short-course treatment for Tuberculosis in Puducherry, Southern India.Settings: Retrospective cohort study; Tuberculosis Unit in District Tuberculosis Centre, Puducherry, India. Materials and Methods: Cohort analysis of patients of registered at the Tuberculosis Unit during 1st and 2nd quarter of the year 2011. Details about sputum conversion, treatment outcome and time of default were obtained from the tuberculosis register.Statistical Analysis: Kaplan-Meier plots & log rank tests.Results: RNTCP targets with respect to success rate (85.7%), death rate (2.7%) and failure rate (2.1%) in new cases have been achieved but the sputum conversion rate (88%) and default rate (5.9%) targets have not been achieved. The overall default rate for all registered TB patients was 7.4%; significantly higher in category II. In retreatment cases registered as treatment after default, the default rate was high (9%). The cumulative default rate; though similar in the initial two months of treatment; was consistently higher in category II as compared to that in category I. Nearly 40% of all defaulters interrupted treatment between the second and fourth month after treatment initiation.Conclusion: Defaulting from treatment is more common among the retreatment cases and usually occurs during the transition phase from intensive phase to continuation phase.
机译：背景：经修订的印度国家结核病控制计划（RNTCP）提高了治愈率目的：本研究从直接观察到的短期治疗的患者的转化率，治疗结果和违约时间模式方面描述了RNTCP下的成就地点：印度南部Puducherry的结核病。印度Puducherry地区结核病中心的结核病科。资料和方法：对2011年第一季度和第二季度在结核病科登记的患者进行队列分析。有关痰液转化，治疗结果和违约时间的详细信息，请从结核病登记表中获取。统计分析：Kaplan-Meier图和结果：达到新病例的成功率（85.7％），死亡率（2.7％）和失败率（2.1％）的RNTCP目标，但痰液转化率（88％）和默认率（尚未达到5.9％的目标。所有登记的结核病患者的总失误率为7.4％;在第二类中明显更高。在违约后注册为治疗的再治疗案例中，违约率很高（9％）。累计违约率;尽管在治疗的头两个月相似; II类患者比I类患者始终更高。几乎有40％的默认患者在治疗开始后的第二个月至第四个月之间中断了治疗。结论：在默认情况下，再治疗病例中更常见于默认情况，通常发生在过渡期从强化阶段到延续阶段。

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