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首页> 外文期刊>Journal of Clinical and Diagnostic Research >The Effect of Oxygen Inhalation Plus Oxytocin Compared with Oxytocin Only on Postpartum Haemorrhage: A Randomized Clinical Trial
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The Effect of Oxygen Inhalation Plus Oxytocin Compared with Oxytocin Only on Postpartum Haemorrhage: A Randomized Clinical Trial

机译：吸氧加催产素与仅催产素相比对产后出血的影响：一项随机临床试验

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Introduction: Post Partum Haemorrhage (PPH) is the leading cause of maternal mortality across the world, mainly in the developing countries.Aim: The present study was conducted with the aim to investigate effect of oxygen inhalation plus oxytocin compared with oxytocin only on PPH.Materials and Methods: This study was a clinical trial which was performed in Shahid Mustafa Khomieni Teaching Hospital of Ilam (western Iran) from April 2012 to Nov 2013. One hundred and twenty pregnant women who were referred to delivery ward for normal vaginal delivery were selected with convenience sampling method and they were randomly assigned into two groups. For both groups management of the third stage of labour was done using 1000CC Ringer and 20 units of Oxytocin. In the intervention group, in addition to the routine administration, 8 liters of oxygen via face mask was used continuously until 2 hours after delivery. Blood loss was determined by regular weighing of the buttocks that were previously weighted. The difference was calculated before and after weighing (1 gram increasing of weight was considered to be equivalent to 1CC blood loss). Data were analysed by SPSS 16 version using Student- t and Chi-square tests.Results: The two groups were homogenous in regard to all the base line variables. The study results indicated that the mean of blood loss were (256.16±97) ml at two hours after delivery in the control group and (149.5±46.49) ml in the intervention group. There was a significant difference between PPH of the two groups (p<0.006).Conclusion: Research findings showed that the use of inspired oxygen during the third stage of labour and oxytocin infusion during 2hours later resulted in a significant decreasing in the amount of bleeding after normal vaginal delivery.
机译：简介：产后出血（PPH）是全世界孕产妇死亡的主要原因，主要是在发展中国家。目的：进行本研究的目的是研究吸氧加催产素与仅催产素相比对PPH的影响。材料和方法：该研究是一项临床试验，于2012年4月至2013年11月在伊拉姆（伊朗西部）的Shahid Mustafa Khomieni教学医院进行。选择了120名被转诊到正常阴道分娩病房的孕妇。采用便利抽样法，将他们随机分为两组。两组的第三产程管理均使用1000CC林格和20单位催产素进行。在干预组中，除了常规给药外，通过面罩连续使用8升氧气，直到分娩后2小时为止。通过定期称重先前称重的臀部来确定失血量。在称重前后计算差异（体重增加1克相当于1CC失血）。使用Student-t和卡方检验通过SPSS 16版本分析数据。结果：两组在所有基线变量方面都是同质的。研究结果表明，对照组在分娩后两小时的平均失血量为（256.16±97）ml，而干预组为（149.5±46.49）ml。两组的PPH之间存在显着差异（p <0.006）。结论：研究结果表明，在分娩的第三阶段使用吸入氧气和在2小时后输注催产素导致出血量显着减少。正常阴道分娩后。

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