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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Association of Intrauterine Device (IUD) and Cervical Neoplasia - A Study in a Poor Nigerian Population
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Association of Intrauterine Device (IUD) and Cervical Neoplasia - A Study in a Poor Nigerian Population

机译：宫内节育器（IUD）与宫颈肿瘤的关系-尼日利亚贫困人口的一项研究

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Introduction: Intrauterine Device (IUD) is a contraceptive method used by women of reproductive age group. However, there are conflicting reports on the association between IUD and cervical neoplasia. These controversies may further hamper the poor uptake of modern contraception in Nigeria.Aim: This study was therefore aimed at evaluating the association between IUD and cervical neoplasia.Materials and Methods: This was a case control study in which Pap smear results of 156 participants on IUD were compared with those of 156 non-users of modern contraception. The participants who were found to have abnormal cervical smear cytology results were further subjected to colposcopy. Biopsy specimens for histology were collected from the participants with obvious cervical lesions or those with suspicious lesions on colposcopy. The results were analysed with descriptive and inferential statistics at 95% level of confidence.Results: Seven (4.5%) and 2(1.3%) of participants using IUD had Cervical Intraepithelial Neoplasia (CIN) 1 and CIN 2 respectively. Also, 5(3.2%) and 1(0.6%) of non-users of modern contraception had CIN 1 and CIN 2 respectively. The prevalence of cervical neoplasia among all the participants was 4.8%. Although, the proportion of women who had CIN was more among participants using IUD than non-users of modern contraception, the difference was not statistically significant.Conclusion: There was no significant association between IUD and cervical neoplasia in this study.
机译：简介：宫内节育器（IUD）是育龄妇女使用的避孕方法。但是，关于宫内节育器与宫颈肿瘤的关系的报道相互矛盾。这些争议可能会进一步阻碍尼日利亚现代避孕措施的普及。目的：本研究旨在评估宫内节育器与宫颈肿瘤的关系。材料与方法：这是一项病例对照研究，其中156名参与者的宫颈涂片检查结果将宫内节育器与156名非现代避孕方法使用者进行比较。被发现宫颈涂片细胞学检查结果异常的参与者需接受阴道镜检查。从阴道镜检查中有明显宫颈病变或可疑病变的参与者收集组织学活检标本。结果以描述性和推论性统计学方法在95％的置信水平下进行分析。结果：使用IUD的参与者中有7（4.5％）和2（1.3％）分别患有宫颈上皮内瘤样变（CIN）1和CIN 2。此外，非避孕药的非使用者中有5（3.2％）和1（0.6％）分别具有CIN 1和CIN 2。在所有参与者中，宫颈肿瘤的患病率为4.8％。尽管使用宫内节育器的女性中有CIN的比例要比不使用现代避孕方法的女性高，但差异无统计学意义。结论：本研究中宫内节育器与宫颈癌的发生没有显着相关性。

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