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首页> 外文期刊>Journal of Clinical and Diagnostic Research >An Update on Recurrent Early Pregnancy Loss: Causes, Controversies and Cure
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An Update on Recurrent Early Pregnancy Loss: Causes, Controversies and Cure

机译:复发性早孕的最新动态:原因,争议和治疗方法

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Recurrent Pregnancy Loss (RPL) is an important reproductive issue, affecting 1-5% of couples. It is characterised by repeated miscarriage, impairing the ability to have a live birth. The proven causes are diverse, such as cytogenetic abnormality, uterine anomalies, antiphospholipid antibody, metabolic and endocrine abnormalities, and about 50% cases of RPL remain still unexplained. To facilitate the diagnosis, different screening tests have been recommended, such as antiphospholipid antibody tests, thyroid stimulating hormone, glucose tolerance test, chromosomal assessment, ultrasound testing etc. RPL is associated with psychological trauma and financial burden. An evidence-based treatment is available for the majority of causes and it is seen that most of the women eventually become pregnant with an appropriate treatment plan, regardless of the cause. It has also been shown that patients presenting no abnormality on various tests may achieve a good rate of live births without special treatment. This study also includes certain controversial aetiologies and unconventional tests. This review touches on the management of various abnormalities in brief. Recurrent pregnancy loss has a significant negative life impact due to its repetitive nature; however, emotional care along with appropriate management improves chances of future pregnancy.
机译:反复流产(RPL)是一个重要的生殖问题,影响了1-5%的夫妻。它的特点是反复流产,削弱了活产的能力。业已证实的原因多种多样,例如细胞遗传异常,子宫异常,抗磷脂抗体,代谢和内分泌异常,约50%的RPL病例仍无法解释。为了促进诊断,建议使用不同的筛查测试,例如抗磷脂抗体测试,甲状腺刺激激素,葡萄糖耐量测试,染色体评估,超声测试等。RPL与心理创伤和经济负担相关。可以对大多数原因进行循证治疗,并且可以看出,大多数妇女最终都怀有适当的治疗计划,无论原因如何。还表明,在各种检查中均未出现异常的患者,无需特殊治疗即可达到很高的活产率。这项研究还包括某些有争议的病因和非常规检验。这篇综述简要地介绍了各种异常的管理。重复性流产由于其重复性,对生活产生重大的负面影响。但是,情感护理和适当的管理可以增加将来怀孕的机会。

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