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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Primary Early Surgical Management of Pancreatic Ascites Complicating Chronic Pancreatitis-A Single Centre Experience
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Primary Early Surgical Management of Pancreatic Ascites Complicating Chronic Pancreatitis-A Single Centre Experience

机译:胰腺腹水并发慢性胰腺炎的早期早期外科手术治疗-单中心经验

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The traditional method of managing Pancreatic Ascites (PA) complicating Chronic Pancreatitis (CP) was with initial conservative treatment which was associated with increased morbidity and mortality.Aim: To describe about the new treatment protocol which lays emphasis on primary early surgical intervention for PA complicating advanced CP cases based on the pathological morphology of the disease instead of an initial trial of conservative treatment.Materials and Methods: This was a prospective observational study of 15 cases of CP with PA managed over a three year period. The approach was guided by the pathological morphology defined by a CECT abdomen and/or Magnetic Resonance Cholangiopancreatography (MRCP). Of the observed 15 cases, imaging showed a dilated Main Pancreatic Duct (MPD) 5-10 mm in 11 cases, ductal disruption in 4/11 cases and pseudocyst in 8/11 cases. These 11 cases underwent primary early direct surgery. Surgery was tailored to the individual case with a combination of internal ductal/pseudocyst drainage and/or distal resection. Resolution of PA and relief of symptoms were the primary outcome measures. Recurrence of PA at one year follow up after surgery was the secondary outcome measure.Results: Resolution of PA and relief of symptoms occurred in all patients in the primary surgery group. The mean duration of hospital stay was 16 days in the primary surgery group with a range of nine to 23 days with no mortality and no disease recurrence after one year of follow up.Conclusion: Primary early direct surgery guided by the MPD morphology (duct diameter >5 mm) in selected patients with CP and PA leads to faster recovery of the patient and it takes care of the primary pathology too.
机译:治疗并发慢性胰腺炎(CP)的胰腺腹水(PA)的传统方法是初始保守治疗,这会增加发病率和死亡率。目标:描述新的治疗方案,该方案侧重于早期早期外科手术材料与方法:这是一项对前瞻性观察性研究,研究了15名在三年内进行过PA的CP病例,根据疾病的病理形态而不是进行保守治疗的初步试验。该方法由CECT腹部和/或磁共振胆胰管造影(MRCP)定义的病理形态学指导。在观察到的15例患者中,影像学检查显示11例主胰管扩张(MPD)5-10 mm,4/11例导管破裂,8/11例假囊肿。这11例患者接受了早期早期直接手术。结合内部导管/假性囊肿引流和/或远端切除术,根据具体情况定制手术。缓解PA和缓解症状是主要的预后指标。术后一年随访时PA的复发是次要的结局指标。结果:初级手术组的所有患者均出现了PA的缓解和症状的缓解。基本手术组的平均住院时间为16天,随访9年至23天,无死亡,无疾病复发。结论:由MPD形态学指导的早期早期直接手术(导管直径> 5 mm)在选定的CP和PA患者中可以使患者恢复得更快,并且还可以照顾到主要的病理。

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