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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Rare Case Report of Neurofibromatosis I in HIV Positive Individual
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A Rare Case Report of Neurofibromatosis I in HIV Positive Individual

机译:HIV阳性个体中一例神经纤维瘤病的罕见病例报告

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Neurofibroma is an uncommon benign tumour of neural tissue origin rarely presenting in the mouth and jaws and thereby attracting the attention of oral physicians. A 22-year-old male patient reported with a complaint of swelling in left middle one third region of face since 8-10 y which was slowly progressive in size. He had history of multiple dark brown pigmentation on skin associated with progressively enlarging multiple small nodular growths over the body and single firm nodular growth in left side of maxilla intraorally. He had history of tuberculosis at the age of one year which was treated completely and since last 2-3 y he was suffering from recurrent episodes of sore throat, fever, diarrhea, abdominal pain with vomiting and excessive weight loss. Radiographic findings showed irregular osteolytic lesions involving ramus and angle of mandible, zygomatic bone and posterior part of maxilla with displacement of teeth with abnormal soft tissue enhancement observed by advance imaging. On serological investigation he was HIV positive and histopathologically, diagnosed with Neurofibromatosis-1. Oral manifestations of neurofibromatosis have been reported in only 4% to 7% of affected persons. This article presents a rarest of rare case report of neurofibromatosis-I in HIV positive individual also involving maxilla, mandible as well as zygomatic arch.
机译:神经纤维瘤是一种罕见的神经组织源性良性肿瘤,很少出现在口腔和颌骨中,因此引起了口腔医师的关注。一名22岁的男性患者报告称,自8-10年以来,面部左中三分之一区域出现肿胀,其大小逐渐进展。他有在皮肤上出现多个暗褐色色素沉着的病史,并伴有逐渐扩大的全身多个小结节状生长和口腔上颌左侧单个结节状长大的生长。他有1岁的结核病病史,已经接受了彻底治疗,并且从最近2-3年开始,他反复出现喉咙痛,发烧,腹泻,腹痛,呕吐和体重减轻的发作。影像学检查结果显示,不规则的溶骨性病变累及右上颌骨,下颌骨,骨和上颌骨后部的角和角,并伴有牙齿移位,软组织异常增强。在血清学检查中,他是HIV阳性且在组织病理学上被诊断为Neurofibromatosis-1。据报道,只有4%至7%的受影响人患有神经纤维瘤病的口腔表现。本文介绍了在HIV阳性个体中也涉及上颌骨,下颌骨和弓的神经纤维瘤病-I的罕见病例报告。

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