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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Association of Serum Vitamin D Levels and Recurrent Wheezing in Children
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Association of Serum Vitamin D Levels and Recurrent Wheezing in Children

机译：儿童血清维生素D水平与反复喘息的关联

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Wheezing is quite frequently observed in preschool children. There are many risk factors responsible for the development of recurrent wheezing; recently, vitamin D has gained significant interest.Aim: To study the association of serum vitamin D (25(OH) D) level and recurrent wheeze in children less than three years of age.Materials and Methods: This was a Case-control study conducted at a tertiary care hospital in New Delhi. Children less than three years with recurrent wheeze along with age matched controls were subjected to analysis of serum vitamin D, calcium, phosphate and alkaline phosphatase levels. The data was analysed to find out an association between the serum levels of vitamin D and recurrent wheezing.Results: A strong association between the low serum Vitamin D levels and the recurrent wheeze (p=0.001) was found. Also, high levels of serum alkaline phosphatase were seen among the children with recurrent wheezes (677 vs 317 IU/L, p<0.001) and it had an inverse relation with serum vitamin D levels (k-0.688).Conclusion: Low serum vitamin D level is strongly associated with recurrent wheezing in preschool children.
机译：学龄前儿童经常观察到喘息。反复发作的喘息有许多危险因素。最近，维生素D引起了人们的极大兴趣。目的：研究3岁以下儿童血清维生素D（25（OH）D）水平与反复喘息的关系。材料与方法：本研究是在新德里一家三级护理医院进行的病例对照研究。小于3岁的反复喘息的儿童以及年龄相匹配的对照组接受了血清维生素D，钙，磷酸盐和碱性磷酸酶水平的分析。分析数据以找出维生素D的血清水平与复发性喘息之间的关联。结果：发现血清维生素D的低水平与复发性喘息之间有很强的关联性（p = 0.001）。此外，在反复喘息的患儿中，血清碱性磷酸酶水平较高（677比317 IU / L，p <0.001），并且与血清维生素D水平呈反比关系（k-0.688）。b结论：低血清维生素D水平与学龄前儿童反复喘息密切相关。

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