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Childhood Onset Nephrotic Syndrome-A Journey Through Two Pregnancies

机译:童年发作肾病综合征-两次怀孕的旅程

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Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema. It is a rare entity in pregnancy, with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach. Pregnancy does not always worsen the existing NS by causing a relapse or disease progression.
机译:肾病综合症(NS),一种独特的肾脏疾病复合体,伴有大量蛋白尿(蛋白排泄> 3.5 gm /天),低白蛋白血症(<30 gm / L)和周围水肿。它是妊娠中罕见的实体,发生率约为0.012-0.025%。并存NS妊娠的报道很少。我们在此报告一例因小变化疾病及其经历两次妊娠的病程的类固醇敏感性儿童期NS。当她在第一次妊娠期间出现NS复发时,她航行了第二次妊娠而没有复发。 NS患者可以通过多学科的方法在母体和围产期取得良好的效果。怀孕并不总是通过引起复发或疾病进展而恶化现有的NS。

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