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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Clinical Spectrum of Rheumatologic Manifestations in HIV Patients: A Study from Southern India
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Clinical Spectrum of Rheumatologic Manifestations in HIV Patients: A Study from Southern India

机译：HIV患者的风湿病临床表现：印度南部的一项研究

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Introduction: HIV infection is a common disease in India anda variety of rheumatological manifestations are known to occurin HIV Infection. Rheumatological manifestations are signifcantcause of morbidity in these patients.Aim: To study the clinical spectrum and prevalence ofrheumatologic manifestations in HIV patients.Materials and Methods: Patients with HIV 1 and 2 attendingthe Infectious disease outpatient department of Medical CollegeHospital, Thiruvananthapuram during the study period (March2009 to March 2010) were assessed by clinical examinationand with relevant laboratory investigations, to diagnosethe rheumatological manifestation. Based on the clinicalmanifestations and investigations a rheumatological diagnosiswas made. Patients with diabetes mellitus, hypothyroidismand other pre-diagnosed rheumatologic illness were excludedfrom the study. Statistical analyses were done using SPSS IBMStatistics 17.0 version and chi-square test.Results: Out of 385 patients, 161 (41.8%) of HIV patients werein the 30-39 years age group. Male and female were 225 (58.4%)and 160 (41.6%) respectively. A total of 276 (71.7%) patientswere receiving antiretroviral therapy (ART). Disease durationof 1-5 year in 174 (45.19%), <1 year in 135 (35.06%) and resthad more than 5 years of disease. A total of 97 (25.2%) of HIVpatients had rheumatological manifestations. HIV Arthralgiawas the most common manifestation affecting 34 patients(35.1%) of the population with rheumatological manifestations.Knee joint was the most common joint which was involved.The other manifestations noted along with percentage wereMyalgia/muscle ache in 18 patients (18.6%), in?ammatoryback pain in 14 patients (14.4%), soft Tissue Rheumatism in12 patients (12.4%), undifferentiated spondyloarthropathyin 11 patients (11.3%), fbromyalgia in 9 patients (9.3%), HIVwasting in 7 patients (7.2%), HIV arthritis in 4 patients (4.1%)and psoas abscess (3.1%). Each of plantar fascitis, psoriaticNail changes, pyomyositis, painful articular syndrome, erythemanodosum and episcleritis constituted about 2.1% each of therheumatological manifestations. Degenerative joint diseaseconstituted 17.5% of the rheumatological manifestations. Onepatient had evidence of tuberculosis of the spine.Conclusion: The rheumatological manifestations are common inHIV Infected patients. HIV arthralgia, myalgia and undifferentiatedspondyloarthropathy are the common manifestations.
机译：简介：HIV感染是印度的一种常见疾病，已知在HIV感染中会发生多种风湿病表现。风湿病表现是这些患者发病的重要原因。目的：研究HIV病人的风湿病表现的临床范围和患病率。材料与方法：HIV 1和2的HIV患者在研究期间就读于特里凡得琅医学院附属医院传染病门诊（于2009年3月至2010年3月进行临床检查和相关实验室检查以评估风湿病表现。基于临床表现和研究，进行了风湿病诊断。该研究排除了患有糖尿病，甲状腺功能减退和其他预先诊断的风湿病的患者。使用SPSS IBMStatistics 17.0版本和卡方检验进行统计分析。结果：在385名患者中，有161名（41.8％）的HIV患者在30-39岁年龄段。男性和女性分别为225（58.4％）和160（41.6％）。共有276名（71.7％）患者接受抗逆转录病毒疗法（ART）。疾病持续时间为1-4年的1-4年为174年（45.19％），小于135年的为1年（35.06％），并且已恢复5年以上的疾病。共有97名（25.2％）HIV患者有风湿病表现。 HIV节肢动物是最常见的表现，影响了34名风湿病表现的患者（35.1％）;膝关节是最常见的受累关节;其他表现形式还包括18％的肌痛/肌肉疼痛（18.6％），腰背痛14例（14.4％），软组织风湿病12例（12.4％），未分化型脊椎关节病11例（11.3％），纤维肌痛9例（9.3％），HIV消瘦7例（7.2％），HIV关节炎4例（4.1％）和腰肌脓肿（3.1％）。足底筋膜炎，银屑病指甲改变，化脓性肌炎，疼痛性关节综合征，红斑回肠炎和巩膜炎分别构成了约2.1％的风湿病学表现。退行性关节疾病占风湿病学表现的17.5％。结论：感染艾滋病毒的患者常见风湿病表现。 HIV关节痛，肌痛和未分化型脊椎关节病是常见表现。

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