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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Effectiveness of Indian Diabetes Risk Score as a Screening Tool for Non-alcoholic Fatty Liver Disease: A Study from Anand, Gujarat, India
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Effectiveness of Indian Diabetes Risk Score as a Screening Tool for Non-alcoholic Fatty Liver Disease: A Study from Anand, Gujarat, India

机译：印度糖尿病风险评分作为非酒精性脂肪肝疾病筛查工具的有效性：来自印度古吉拉特邦阿南德的一项研究

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Introduction: Non-alcoholic fatty liver disease (NAFLD) iswidely prevalent in the Gujarati population and also shares riskfactors with other Non-communicable diseases (NCDs) suchas diabetes, obesity, and metabolic syndrome. Hence, moreestablished screening tools like Indian Diabetes Risk Score(IDRS) may be considered for screening of NAFLD.Aim: To evaluate the prevalence of NAFLD in Anand, Gujaratand to assess whether IDRS may be used as a screening toolfor NAFLD in Gujarat.Materials and Methods: A cross-sectional observational studyinvolving 217 participants with a mean age of 56.83±11.39years was conducted at the Health Check-up department atShree Krishna Hospital, Anand, Gujarat, India. Participantswere classified as having NAFLD using the USG parameters.Their IDRS score was calculated and applied to the participantsfollowing which its ability to screen NAFLD was compared withthat of screening tools such as BMI, W/H Ratio and HBA1c,and risk factors associated with NAFLD. The IDRS wasclassified as high (≥60), medium (30-50), and low (<30) risk.Using univariate analysis in STATA (14.2), factors associatedwith NAFLD were identified, following which stepwise logisticregression analysis was performed. Differences between therisk groups of IDRS were tested using the chi-square test andanalysis of variance.Results: The prevalence of NAFLD (37.79%) was signifcantlyhigher among those with a high (67.7%) and medium IDRS(16%) compared to the low IDRS group (7.4%) (trend chi-square;p<0.001). In stepwise logistic regression, IDRS was associatedwith NAFLD with an adjusted odds ratio of 1.03 (95% confdenceinterval 1.00-1.07 with a p-value of 0.036), even after adjustingfor potential confounders.Conclusion: IDRS score can be used to screen for theprevalence of NAFLD.
机译：简介：非酒精性脂肪肝疾病（NAFLD）在古吉拉特邦（Gujarati）人群中普遍存在，并且与其他非传染性疾病（NCD）具有共同的危险因素，例如糖尿病，肥胖症和代谢综合征。因此，可以考虑使用更成熟的筛查工具，例如印度糖尿病风险评分（IDRS）来筛查NAFLD。目的：评估古吉拉特邦阿南德市NAFLD的患病率，评估IDRS是否可以用作古吉拉特邦NAFLD筛查工具。方法：在印度古吉拉特邦阿南德的Shree Krishna医院的健康检查部门对217名平均年龄为56.83±11.39岁的参与者进行了横断面观察研究。使用USG参数将参与者分类为具有NAFLD。计算其IDRS得分并将其应用于参与者，然后将其筛选NAFLD的能力与BMI，W / H比和HBA1c等筛选工具的能力以及与NAFLD相关的危险因素进行比较。将IDRS分为高（≥60），中（30-50）和低（<30）风险。使用STATA（14.2）中的单变量分析，确定与NAFLD相关的因素，然后进行逐步logistic回归分析。通过卡方检验和方差分析检验了IDRS风险组之间的差异。结果：高IDRS（67.7％）和中IDRS（16％）的人群中，NAFLD的患病率（37.79％）显着更高IDRS组（7.4％）（趋势卡方; p <0.001）。在逐步logistic回归中，即使在对潜在的混杂因素进行调整之后，IDRS与NAFLD的调整比值比为1.03（95％置信区间为1.00-1.07，p值为0.036）。结论：IDRS得分可用于筛查患病率NAFLD。

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