Asymmetric transcription of R plasmid NR1 in Proteus mirabilis.

E R Appelbaum; R H Rownd

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Asymmetric transcription of R plasmid NR1 in Proteus mirabilis.

机译：R质粒NR1在奇异变形杆菌中的不对称转录。

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The composite R plasmid NR1, its resistance transfer factor which specifies resistance to tetracycline (RTF-Tc component), and its r-determinants component were each denatured and centrifuged to equilibrium in CsCl density gradients containing polyuridylic acid-polyguanidylic acid. The complementary deoxyribonucleic acid strands of NR1 and the complementary strands of the RTF-Tc component could be separated by this technique because of a threefold difference in polyuridylic acid-polyguanidylic acid binding to the strands of the RTF-Tc component. The two strands of the r-determinants component bound equal amounts of polyuridylic acid-polyguanidylic acid. Hybridization of single strands of plasmid deoxyribonucleic acid with in vivo-labeled ribonucleic acid from Proteus mirabilis containing NR1 indicated that transcription within the RTF-Tc component is from the NR1 strand which preferentially binds polyuridylic acid-polyguanidylic acid, whereas transcription within the r-determinants component is predominantly from the complementary strand.

机译：复合R质粒NR1，指定四环素抗性的抗性转移因子（RTF-Tc组分）及其r决定簇组分均经过变性，并在含有聚尿苷酸-聚鸟苷酸的CsCl密度梯度中离心至平衡。 NR1的互补脱氧核糖核酸链与RTF-Tc组分的互补链可以通过此技术进行分离，因为与RTF-Tc组分的链结合的聚尿苷酸-聚鸟苷酸的三倍差异。 r-决定簇组分的两条链结合等量的聚尿苷酸-聚鸟苷酸。质粒脱氧核糖核酸单链与体内含有NR1的变形杆菌的体内标记核糖核酸杂交表明，RTF-Tc组分内的转录来自NR1链，后者优先结合聚尿苷酸-聚鸟苷酸，而r-决定簇内的转录组分主要来自互补链。

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《Journal of bacteriology》 |1979年第3期|共6页
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E R Appelbaum; R H Rownd;
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1. Asymmetric transcription of R plasmid NR1 in Proteus mirabilis. [J] . E R Appelbaum, R H Rownd Journal of bacteriology . 1979,第3期

机译：R质粒NR1在奇异变形杆菌中的不对称转录。
2. New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. [J] . Wang M, Guo Q, Xu X Antimicrobial agents and chemotherapy. . 2009,第5期

机译：在奇异变形杆菌的临床分离物中发现了新的质粒介导的喹诺酮抗性基因qnrC。
3. Evaluation of screening methods to detect plasmid-mediated AmpC in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis. [J] . Tan TY, Ng LS, He J Antimicrobial agents and chemotherapy. . 2009,第1期

机译：评价在大肠杆菌，肺炎克雷伯菌和奇异变形杆菌中检测质粒介导的AmpC的筛选方法。
4. Non-Invasive Quantification of Plasmid Dynamics:Biofilm Formation Effect on Plasmid conjugational plasmid transfer [C] . Hongyan Ma, James.D. Bryers Annual meeting of the Society for Biomaterials . 2011

机译：质粒动力学的无创定量：生物膜形成对质粒结合质粒转移的影响
5. Contributions of the Rcs Phosphorelay and FlhD4C 2 to Swarming Behavior in Proteus mirabilis. [D] . Howery, Kristen E. 2016

机译：Rcs Phosphorelay和FlhD4C 2对奇异变形杆菌的成群行为的贡献。
6. Asymmetric transcription of R plasmid NR1 in Proteus mirabilis. [O] . E R Appelbaum, R H Rownd 1979

机译：R质粒NR1在奇异变形杆菌中的不对称转录。
7. Double Synergy Differential Test for detection of plasmid-mediated AmpC-type beta-lactamases in Proteus mirabilis. [O] . C. Sabia, M. Sarti, E. Mantengoli, 2010

机译：双重协同差异检测用于检测变形杆菌中质粒介导的AmpC型β-内酰胺酶。
8. Survival of Plasmid-Containing Strains of 'Escherichia coli' in Soil: Effect of Plasmid Size and Nutrients on Survival of Hosts and Maintenance of Plasmids [R] . Devanas, M. A. , Rafaeli-Eshkol, D. , Stotzky, G. 1986

机译：含有质粒的'大肠杆菌'菌株在土壤中的存活：质粒大小和营养成分对宿主存活和质粒维持的影响

Asymmetric transcription of R plasmid NR1 in Proteus mirabilis.

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