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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Exophiala jeanselmei and Rhizopus oryzae Co-infection Post Renal Transplant
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Exophiala jeanselmei and Rhizopus oryzae Co-infection Post Renal Transplant

机译：肾移植后 Exophiala jeanselmei 和 Rhizopus oryzae 共感染

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摘要

Invasive fungal infections are associated with morbidity and mortality in immunocompromised patients. Dematiaceous fungi are being increasingly recognised as human pathogens, particularly in transplant recipients. However, most cases of dematiaceous fungal infections after organ transplantation have been reported as sole aetiological agents. We report a case of fatal, disseminated phaeohyphomycosis with rhinocerebral mucormycosis in post renal transplant patient. Quick diagnosis is challenging and inspite of aggressive management with a combination of surgical and medical therapies, the outcome is poor. Amphotericin B remains the cornerstone in the medical management of mucormycosis and itraconazole in phaeohyphomycosis, still we are short of drugs to fight against such catastrophic organisms.
机译：侵袭性真菌感染与免疫功能低下患者的发病率和死亡率有关。越来越多的人认为皮损真菌是人类病原体，尤其是在移植受体中。然而，据报道，大多数器官移植后皮肤真菌感染的病例是唯一的病因。我们报告了在肾移植后患者中发生的致命性，分散性伴肺犀的真菌性真菌病。快速诊断具有挑战性，尽管通过外科手术和药物治疗相结合进行积极的治疗，但效果差。两性霉素B仍然是毛霉菌病和伊曲康唑在疏忽性真菌病的药物治疗中的基石，但我们仍然缺乏抗击这种灾难性生物的药物。

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