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首页> 外文期刊>Journal of bacteriology >Fructose 1,6-bisphosphate aldolase activity is essential for synthesis of alginate from glucose by Pseudomonas aeruginosa.
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Fructose 1,6-bisphosphate aldolase activity is essential for synthesis of alginate from glucose by Pseudomonas aeruginosa.

机译:1,6-二磷酸果糖醛缩酶的活性对于铜绿假单胞菌由葡萄糖合成藻酸盐至关重要。

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摘要

We have isolated a mutant of Pseudomonas aeruginosa deficient in fructose 1,6-bisphosphate aldolase activity. This mutant, similar to the mutants deficient in any of the Entner-Doudoroff pathway enzymes, does not allow appreciable alginate formation from glucose and gluconate, but allows alginate synthesis from mannitol and fructose. This suggests that glucose and gluconate must be converted to fructose 1,6-bisphosphate via the Entner-Doudoroff pathway enzymes and fructose 1,6-bisphosphate aldolase.
机译:我们已经分离出缺乏果糖1,6-二磷酸醛缩酶活性的铜绿假单胞菌的突变体。该突变体与缺乏任何Entner-Doudoroff途径酶的突变体相似,不允许从葡萄糖和葡萄糖酸盐中形成可观的藻酸盐,但允许从甘露醇和果糖中合成藻酸盐。这表明葡萄糖和葡萄糖酸必须通过Entner-Doudoroff途径酶和果糖1,6-二磷酸醛缩酶转化为果糖1,6-二磷酸酯。

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